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Vilazodone
go.drugbank.com/drugs/DB06684ApprovedInvestigationalVilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight ga...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsLaquinimod
go.drugbank.com/drugs/DB06685InvestigationalLaquinimod is an immunomodulator developed by Active Biotech and produced by Teva Pharmaceutical Industries. It is currently under development in phase III trials for treatment of multiple sclerosis as an oral therapy, like fingolimod. I...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesArtemether
go.drugbank.com/drugs/DB06697ApprovedInvestigational</i> and may be used to treat infections caused by <i>P. falciparum</i> and unidentified <i>Plasmodium</i> species, including infections acquired in chloroquine-resistant areas.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersFesoterodine
go.drugbank.com/drugs/DB06702ApprovedFesoterodine is an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesMethyltestosterone
go.drugbank.com/drugs/DB06710ApprovedInvestigationalA synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methylt...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNorelgestromin
go.drugbank.com/drugs/DB06713ApprovedInvestigationalNorelgestromin is a progestin used as the progestational component of combined hormonal contraceptives. It is administered transdermally in combination with the estrogen ethinyl estradiol, delivering both hormones systemically over a 7-d...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEnclomiphene
go.drugbank.com/drugs/DB06735InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesAceclofenac
go.drugbank.com/drugs/DB06736ApprovedAceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher ant...
Mixtures: ZERODOL PCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesKetobemidone
go.drugbank.com/drugs/DB06738InvestigationalKetobemidone is a powerful opioid analgesic. It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids. The most commonly cited equalisation ratio for analgesic dose...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesSeratrodast
go.drugbank.com/drugs/DB06739ExperimentalSeratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Inhibitors