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Displaying results 1521 - 1530 of 10000 in total
  1. Drug

    Selumetinib

    go.drugbank.com/drugs/DB11689
    ApprovedInvestigational

    NF-1 is considered rare, with an estimated incidence of 1/3000 individuals. … [A193611] "The novel MEK 1/2 inhibitor, selumetinib, was initially approved solely for the treatment of pediatric patients with Neurofibromatosis type 1 (NF-1) and symptomatic, inoperable plexiform

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  2. Drug

    Naldemedine

    go.drugbank.com/drugs/DB11691
    ApprovedInvestigational

    It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier.

    Categories: Heterocyclic Compounds with 4 or More Rings
  3. Drug

    Tropisetron

    go.drugbank.com/drugs/DB11699
    ApprovedInvestigationalWithdrawn

    As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: NAVOBAN 5 MG 1 AMPUL, Navoban 5 mg - Kapseln
  4. Drug

    Amenamevir

    go.drugbank.com/drugs/DB11701
    Investigational

    Amenamevir has been used in trials studying the treatment of Herpes Zoster, Herpes Simplex, Herpes Genitalis, and Safety of Amenamevir.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  5. Drug

    Antineoplaston A10

    go.drugbank.com/drugs/DB11702
    Investigational

    Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.

    Synonyms: BENZENEACETAMIDE, N-(2,6-DIOXO-3-PIPERIDINYL)-, (S)-, BENZENEACETAMIDE, N-((3S)-2,6-DIOXO-3-PIPERIDINYL)-Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Acetyl hexapeptide-3

    go.drugbank.com/drugs/DB11709
    Investigational

    Argireline has been used in trials studying the treatment of wrinkles.

    Mixtures: HydroGold 9Synonyms: Hexapeptide 3, Acetyl hexapeptide-3
  7. Drug

    Trigonellamide

    go.drugbank.com/drugs/DB11710
    Investigational

    Trigonellamide is under investigation in clinical trial NCT01930240 (The Safety of a Hypolipidemic Agent in Healthy Normal Volunteers).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-MNA
  8. Drug

    Navarixin

    go.drugbank.com/drugs/DB11711
    Investigational

    Navarixin has been investigated for the treatment of Asthma.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Ruzasvir

    go.drugbank.com/drugs/DB11713
    Investigational

    Ruzasvir has been used in trials studying the treatment of Hepatitis C, Hepatitis C, Chronic, and Hepatitis C Infection.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Durvalumab

    go.drugbank.com/drugs/DB11714
    ApprovedInvestigational

    Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. … [A192789] Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture,[L12621] durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote

    Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: IMFINZI® 50 MG/ML CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN, IMFINZI 120 MG/2.4 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET