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Tick-borne encephalitis vaccine (whole virus, inactivated)
go.drugbank.com/drugs/DB16611ApprovedInvestigationalTick-borne encephalitis (TBE) is a disease caused by the TBE virus (TBEV), transmitted by ticks from the genus _Ixodes_. The disease course is variable. … [A237505] TBE often manifests in a biphasic manner, with patients experiencing a flu-like illness followed by a variable asymptomatic period and then a second phase characterized by various neurological
D-Proline
go.drugbank.com/drugs/DB02853ExperimentalThese amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity [A19263]. … D-amino acids have been found in relatively high abundance in human plasma and saliva [A19262].
Stannous fluoride
go.drugbank.com/drugs/DB11092ApprovedInvestigationalIt manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing gingival inflammation and bleeding [A19582, A19583] through its potential broad-spectrum antibiotic
Fluciclatide
go.drugbank.com/drugs/DB14842InvestigationalThe conditions targeted by [18F]Fluciclatide in these studies include high-grade glioma, lung cancer, and kidney neoplasms
Haemagglutinin-strain B (Victoria-like)
go.drugbank.com/drugs/DB15473ApprovedMixtures: Fluzone High-dose QuadrivalentSodium phosphate, monobasic
go.drugbank.com/drugs/DB09449ApprovedInvestigationalSodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Dapsone
go.drugbank.com/drugs/DB00250ApprovedInvestigationalA sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.
Benznidazole
go.drugbank.com/drugs/DB11989ApprovedInvestigationalBenznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.
Torcetrapib
go.drugbank.com/drugs/DB06281InvestigationalTorcetrapib (CP-529414, Pfizer) was developed to treat hypercholesterolemia but its development was halted in 2006 when phase III studies showed excessive mortality in the treatment group receiving a combination
Ritlecitinib
go.drugbank.com/drugs/DB14924ApprovedInvestigationalIn June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further approved by the EMA in September 2023.