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Displaying results 1531 - 1540 of 1909 in total
  1. Drug

    OTL-102

    go.drugbank.com/drugs/DB18642
    Experimental

    It is being investigated for the treatment of X-linked chronic granulomatous disease.

  2. Drug

    OTL-203

    go.drugbank.com/drugs/DB18643
    Investigational

    OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.

    Synonyms: Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene
  3. Drug

    Viltolarsen

    go.drugbank.com/drugs/DB15005
    ApprovedInvestigational

    Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function

  4. Drug

    Fucose

    go.drugbank.com/drugs/DB15236
    Investigational

    Fucose is under investigation in clinical trial NCT03354533 (Study of ORL-1F (L-fucose) in Patients With Leukocyte Adhesion Deficiency Type II).

    Synonyms: L-FUCOSE
  5. Drug

    Umbilical Cord Blood Hematopoietic Stem Cells

    go.drugbank.com/drugs/DB15723
    Investigational

    Cord blood transplants have been used to treat conditions from aplastic anemia, B-thalassemia, X-linked lymphoproliferative syndrome, Hunter’s syndrome, acute lymphoid leukemia, chronic myeloid leukemia

  6. Drug

    Nezastomig

    go.drugbank.com/drugs/DB19061
    Investigational

    Nezastomig is under investigation in clinical trial NCT06085664 (A Pilot Presurgical Trial of REGN5678 (Anti-psma X CD28) in Patients With High-risk, Localized Prostate Cancer Followed by Radical Prostatectomy

  7. Drug

    UCB7362

    go.drugbank.com/drugs/DB17096
    Experimental

    UCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria.

  8. Drug

    L-3972-T

    go.drugbank.com/drugs/DB17441
    Experimental

    L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.

    Synonyms: ISA101B component L-3972-T, Human Papilloma Virus (HPV) Type 16 E6/E7 Synthetic Long Peptide (SLP) Vaccine Component L-3972-T
  9. Drug

    Red blood cell-encapsulated L-asparaginase

    go.drugbank.com/drugs/DB17477
    Investigational

    Red blood cell-encapsulated L-asparaginase is [Asparaginase Escherichia coli] encapsulated inside donor-derived red blood cells, which target cancer cells capable of altering asparagine and glutamine metabolism

    Synonyms: RBC-encapsulated l-asparaginase, Erythrocyte encapsulated l-asparaginase
  10. Drug

    6-diazo-5-oxo-L-norleucine

    go.drugbank.com/drugs/DB17537
    Investigational

    6-diazo-5-oxo-L-norleucine is a broad-acting glutamine antagonist.

    Synonyms: 6-Diazo-5-oxo-L-norleucine