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Displaying results 1541 - 1550 of 7181 in total
  1. Drug

    Denosumab

    go.drugbank.com/drugs/DB06643
    ApprovedInvestigational

    It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. … Two denosumab biosimilars—Wyost® (denosumab-bbdz) [L53063] and Jubbonti® (denosumab-bbdz)[L53058]—were approved by the FDA in March 2024 for all indications of the reference products Xgeva® and Prolia®

  2. Drug

    Bupivacaine

    go.drugbank.com/drugs/DB00297
    ApprovedInvestigational

    Bupivacaine is a widely used local anesthetic agent.

    Synonyms: 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamideMixtures: Physicians EZ Use M-pred, Physicians EZ Use M-pred
  3. Drug

    Lofexidine

    go.drugbank.com/drugs/DB04948
    ApprovedInvestigational

    [T210] Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and have fewer side effects than clonidine. … [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018.[L2794]

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  4. Indication

    Dementia, Multi-Infarct

    go.drugbank.com/conditions/DBCOND0006170
    Drugs: Choline alfoscerate
    Synonyms: Vascular dementia as a result of infarction of the brain due to vascular disease, including hypertensive cerebrovascular disease.
  5. Drug

    Selenium

    go.drugbank.com/drugs/DB11135
    ApprovedInvestigationalVet approved

    Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen

    Mixtures: Dry Form Vitamin E 400iu With Selenium 100mcg, ADDAMEL N
  6. Drug

    Beeswax

    go.drugbank.com/drugs/DB11600
    Approved

    Beeswax is used as a stiffening agent in ointments and creams, and enables water to be incorporated to produce water-in-oil emulsions. … The wax obtained from the honeycomb of the bee. It consists primarily of myricyl palmitate, cerotic acid esters and some high-carbon paraffins.

  7. Drug

    Rimegepant

    go.drugbank.com/drugs/DB12457
    ApprovedInvestigational

    and cardiovascular disease due to their vasoconstrictive properties. … safer for use in patients with contraindications to standard therapy.

  8. Drug

    Technetium Tc-99m disofenin

    go.drugbank.com/drugs/DB09164
    ApprovedWithdrawn

    for liver uptake) as are other tracers from the iminodiacetic acid. … Technetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with no known pharmacologic actions at the doses recommended.

    Synonyms: Technetium Tc 99m Disofenin, Technetium Tc-99m disofenin
  9. Drug

    Flupentixol

    go.drugbank.com/drugs/DB00875
    ApprovedInvestigationalWithdrawn

    It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. … It is approved for use in Canada and other countries around the world, but not in the US.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  10. Indication

    Neurocognitive Disorders

    go.drugbank.com/conditions/DBCOND0064252
    Drugs: Zuclopenthixol
    Synonyms: Cognitive disorder due to disorder, Mental disorder NOS due to known physiological condition