Search

Displaying results 1541 - 1550 of 5899 in total
  1. Drug

    Celiprolol

    go.drugbank.com/drugs/DB04846
    ApprovedInvestigationalWithdrawn

    Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. … This study demonstrated decreased incidence of arterial rupture or dissection (a specific type of arterial rupture in which the layers of the vessel separate prior to complete failure of the artery wall

  2. Drug

    Aurothioglucose

    go.drugbank.com/drugs/DB09121
    ApprovedWithdrawn

    Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis [A32326]. … Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis.

  3. Drug

    Agalsidase alfa

    go.drugbank.com/drugs/DB15874
    ApprovedInvestigational

    While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta. … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta].

  4. Drug

    Efmoroctocog alfa

    go.drugbank.com/drugs/DB11607
    ApprovedInvestigational

    Efmoroctocog alfa is a first commercially available rFVIII-Fc fusion protein (rFVIIIFc) where the conjugated molecule of rFVIII to polyethylene glycol is covalently fused to the dimeric Fc domain of human … To date, no confirmed inhibitory autoantibodies were seen in previously treated patients included in clinical studies and treatment-emergent adverse events were generally consistent with those expected

  5. Drug

    ATX-201

    go.drugbank.com/drugs/DB05765
    Investigational

    The company announced the decision to discontinue its ATX-201 clinical program for actinic keratosis. … ATX-201 is one of a family of novel compounds that inhibits microtubule polymerization. It is developed by Kythera Biopharmaceuticals, Inc. for the treatment of actinic keratosis.

  6. Drug

    LX201

    go.drugbank.com/drugs/DB04943
    Investigational

    LX201 is a silicone matrix ocular implant that provides sustained release of cyclosporine A (CsA) locally to the eye over the course of one year.

  7. Drug

    Tropicamide

    go.drugbank.com/drugs/DB00809
    Approved

    [L32178] Oral tropicamide has been investigated as a potential drug to relieve sialorrhea in patients with Parkinson's Disease.[A229958] … [A230103] Usually available in ophthalmic formulations, tropicamide is used to cause mydriasis and cycloplegia for eye exams or ocular procedures.

    Products: MINIMS TROPICAMIDE EYE DROPS 1% w/v
  8. Drug

    Gadodiamide

    go.drugbank.com/drugs/DB00225
    ApprovedInvestigational

    [A263101] However, since linear, non-ionic GBCA is less stable than macrocyclic or ionic GBCA, gadodiamide can potentially lead to more gadolinium retention in the brain and thus more likely to cause side … [A263096] Approved by the FDA in 1993, gadodiamide is the first non-ionic GBCA to be used.

  9. Drug

    Esculin

    go.drugbank.com/drugs/DB13155
    Approved

    Esculin belongs to the family of Glycosyl Compounds. … These are carbohydrate derivatives in which a sugar group is bonded through its anmoeric carbonA to another group via a C-, S-,N-,O-, or Se- glycosidic bond.

    Synonyms: 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one, Esculetin 6-O-glucoside
  10. Drug

    Chloramphenicol

    go.drugbank.com/drugs/DB00446
    ApprovedInvestigationalVet approvedWithdrawn

    It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. … (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due to the high risk of fatal aplastic anemia associated with this

    Mixtures: CLOXONA-OProducts: Kloraxin Eye Ointment 1% w/w, ENCLOR EAR DROPS 5% W/V