Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California... Esculin belongs to the family of Glycosyl Compounds.
- Mechanism
- Curator reviewed
The main activities of Esculine focus on capillary protection, as it improves capillary permeability and fragility. It is reported to inhibit catabolic enzymes such as hyaluronidase and collagenase, thus preserving the integrity of the perivascular connective tissue. Esculine also showed good antioxidant properties, protecting triglycerides against auto-oxidation at high temperatures. The antioxidant property might as well explain some of the anti-inflammatory activity of the product, making it a suitable product for after sun treatments, for example.
- Primary indication
- As medication, esculin is sometimes used as a vasoprotective agent.Curator reviewed · 6 structured indications
- Formula / weight
- C15H16O9 · 340.284 g/mol (avg)
- First approval
- Canada, 2003
- Also known as
- Aesculin · Esculetin 6-O-glucoside · Esculoside
- Brand names
Resolves to
XHCADAYNFIFUHF-TVKJYDDYSA-NSMILESOC[C@H]1O[C@@H](OC2=C(O)C=C3OC(=O)C=CC3=C2)[C@H](O)[C@@H](O)[C@@H]1OWhat you can answer from here — as of August 30, 2026
Which drugs share a target with Esculin, and which of those have an active Phase 3 trial?
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