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Displaying results 1561 - 1570 of 8410 in total
  1. Drug

    Promethazine

    go.drugbank.com/drugs/DB01069
    ApprovedInvestigational

    Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of [phenothiazine] that was developed in France in 1946.

    Mixtures: Promethazine DM, Promethazine DMCategories: Dopamine D2 Receptor Antagonists, P-glycoprotein inhibitors
  2. Drug

    Pine tar

    go.drugbank.com/drugs/DB15840
    ApprovedWithdrawn

    Synonyms: Pine tar, Archangel tarMixtures: Mild Multi-tar Plus Shampoo, Regular Multi-tar Plus Shampoo
  3. Drug

    Levorphanol

    go.drugbank.com/drugs/DB00854
    Approved

    A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.

  4. Drug

    SynKIR-110

    go.drugbank.com/drugs/DB17365
    Investigational

    SynKIR-110 are autologous T cells genetically engineered to express an anti-mesothelin killer immunoglobulin-like receptor-chimeric antigen receptor (KIR-CAR).

    Synonyms: SynKIR-meso CAR-T cells
  5. Drug

    Physostigmine

    go.drugbank.com/drugs/DB00981
    Approved

    It can be applied topically to the conjunctiva. … It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.

  6. Drug

    Acetyl sulfisoxazole

    go.drugbank.com/drugs/DB14033
    ApprovedVet approved

    This process causes an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, resulting in cell growth arrest and cell death [L2788]. … Sulfisoxazole acetyl is an ester of _sulfisoxazole_, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity.

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  7. Drug

    Methadone

    go.drugbank.com/drugs/DB00333
    ApprovedInvestigational

    [A185888,A185891,A185897] Compared with [morphine], the gold standard reference opioid, methadone also acts as an agonist of κ- and σ-opioid receptors, as an antagonist of the N-methyl-D-aspartate (NMDA … Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist.

    Synonyms: dl-MethadoneCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  8. Drug

    AVR-RD-01

    go.drugbank.com/drugs/DB17651
    Investigational

    AVR-RD-01 is an investigational _ex vivo_ lentiviral gene therapy developed by AVROBIO Inc. … AVR-RD-01 is being investigated for Fabry Disease.[L45963, L45968]

  9. Drug

    Magnesium silicate

    go.drugbank.com/drugs/DB13249
    ApprovedWithdrawn

    It is the magnesium salt of silicic acid containing an unspecified amount of water. The molecular formula can be expressed more clearly as MgSiO3.xH2O. … [L2603] Under the FDA, magnesium silicate is determined as a member of the substances generally recognized as safe (GRAS) to be used as an anticaking agent.[L2605]

  10. Drug

    2-deoxyglucose

    go.drugbank.com/drugs/DB08831
    Investigational

    Therapeutically, 2-deoxyglucose is an investigational drug that is being studied as an anticancer and antiviral agent. … As an experimental drug, 2-deoxyglucose was demonstrated to work as an anticonvulsant in temporal lobe epilepsy.

    Synonyms: 2-DG, 2-deoxy-D-glucose