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Oxitriptan
go.drugbank.com/drugs/DB02959ApprovedInvestigationalNutraceuticalWithdrawnoccurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in the United Kingdom, United States and Canada as a dietary supplement for use as an
Brilliant blue G
go.drugbank.com/drugs/DB15594ApprovedBrilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.
Lindane
go.drugbank.com/drugs/DB00431ApprovedWithdrawnAn organochlorine insecticide that has been used as a pediculicide and a scabicide. … Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment.
Human cord blood hematopoietic progenitor cell
go.drugbank.com/drugs/DB11054ApprovedHuman cord blood hematopoietic progenitor cells can be collected from both related or unrelated donors. … Hemacord is marketed in the U.S. as an allogeneic cord blood hematopoietic progenitor cell therapy for intravenous use.
PF-4191834
go.drugbank.com/drugs/DB11645InvestigationalPF-4191834 has been investigated for the basic science of Asthma.
PF-07799933
go.drugbank.com/drugs/DB17489InvestigationalPF-07799933 is a BRAF class 2 inhibitor developed by Pfizer.
CA-170
go.drugbank.com/drugs/DB15772InvestigationalCA-170 is a selective, small molecule inhibitor of PD-L1.
Levocabastine
go.drugbank.com/drugs/DB01106ApprovedLevocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.
Aminophenazone
go.drugbank.com/drugs/DB01424ApprovedWithdrawnThe FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.[A254242,L43942] … In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesConjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigationalThe conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material. Both of these products are later con...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates