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Foreskin keratinocyte (neonatal)
go.drugbank.com/drugs/DB10772ApprovedThe defining moment in skin culture was in 1975 when Rheinwald and Green successfully grew human keratinocytes on lethally irradiated murine fibroblasts. … To construct a "living" alternative, a dermal substitute based on collagen I gel was created with mesenchymal cells such as fibroblasts.
Benzylpenicilloyl polylysine
go.drugbank.com/drugs/DB00895ApprovedInvestigationalThe quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects. … Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy.
Categories: combinations of penicillinsLisocabtagene maraleucel
go.drugbank.com/drugs/DB16582ApprovedInvestigational[A228493] However, data on the efficacy of CAR T-cell therapies on less severe forms of B-cell lymphoma are lacking. … [A228493] Lisocabtagene maraleucel was granted FDA approval on 5 February 2021 [L31583] and EC approval on 5 April 2022.[L42210] It was later granted Health Canada approval on 6 May 2022.
Halothane
go.drugbank.com/drugs/DB01159ApprovedVet approvedWithdrawnA nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly.
Ziconotide
go.drugbank.com/drugs/DB06283ApprovedInvestigationalsynthesized without loss of proper bond formation or structural elements. … [A202829, A202835, A202838, A202841, A202850, A202859, L13389] Ziconotide was granted FDA approval on December 28, 2004 for marketing by TerSera therapeutics LLC. under the name Prialt.
Categories: Compounds used in a research, industrial, or household setting, Analgesics, Non-NarcoticSafinamide
go.drugbank.com/drugs/DB06654ApprovedInvestigationalSafinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: XADAGO 100 MG TABLETASRECUBIERTAS CON PELÍCULA, XADAGO 50 MG TABLETAS RECUBIERTAS CON PELÍCULALasofoxifene
go.drugbank.com/drugs/DB06202ApprovedInvestigationalWithdrawnIt is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment of vaginal atrophy. … Ligand Pharmaceuticals signed a license agreement with Sermonix Pharmaceuticals for the development and commercialization of oral lasofoxifene in the USA.
Categories: Sex Hormones and Modulators of the Genital SystemTetrabenazine
go.drugbank.com/drugs/DB04844ApprovedIt is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008. … A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders.
Synonyms: 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-oneEugenol
go.drugbank.com/drugs/DB09086ApprovedInvestigationalThere are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache. … Its exact mechanism of action is unknown, however, it has been shown to interfere with action potential conduction.
Categories: Compounds used in a research, industrial, or household settingOlopatadine
go.drugbank.com/drugs/DB00768ApprovedAn ophthalmic solution of olopatadine was approved by the FDA and European Union for the treatment of seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. … It is a structural analog of [doxepin], which has a minimal anti-allergic activity.
Categories: Histamine H1 Antagonists, Non-SedatingProducts: OLOPHARM-O, OLOFTAL UD