Eugenol is a phenol used for the temporary relief of toothaches. Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves.
- Mechanism
- Curator reviewed
The exact mechanism of action of eugenol is unknown. However, eugenol has been shown to interrupt action potentials, which may be involved in its anti-pain activity. Research has also shown eugenol to have anti-inflammatory, neuroprotective, antipyretic, antioxidant, antifungal and analgesic properties.
- Primary indication
- Eugenol is not currently available in any FDA-approved drug products.Curator reviewed · 7 structured indications
- Formula / weight
- C10H12O2 · 164.2011 g/mol (avg)
- First approval
- Canada, 1970 · United States, 2012
- Code names
- FEMA NO. 2467 · NSC-209525 · NSC-8895
Resolves to
Clinical / RWD
Structure
InChIKey
RRAFCDWBNXTKKO-UHFFFAOYSA-NSMILESCOC1=C(O)C=CC(CC=C)=C1What you can answer from here — as of September 23, 2026
5Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Eugenol, and which of those have an active Phase 3 trial?
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