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Displaying results 1561 - 1570 of 10000 in total
  1. Drug

    QAV-680

    go.drugbank.com/drugs/DB11658
    Investigational

    QAV680 has been used in trials studying the treatment of Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis.

    Categories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Psilocybin

    go.drugbank.com/drugs/DB11664
    Investigational

    Psilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.

    Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    SP-8203

    go.drugbank.com/drugs/DB11670
    Investigational

    SP-8203 has been used in trials studying the treatment of Ischemic Stroke.

    Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    AZD-4877

    go.drugbank.com/drugs/DB11671
    Investigational

    AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Equol

    go.drugbank.com/drugs/DB11674
    Investigational

    Equol has been used in trials studying the treatment of Breast Cancer.

    Synonyms: S-equolCategories: Heterocyclic Compounds, 2-Ring
  6. Drug

    PF-06282999

    go.drugbank.com/drugs/DB11683
    Investigational

    Pf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects).

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Selumetinib

    go.drugbank.com/drugs/DB11689
    ApprovedInvestigational

    NF-1 is considered rare, with an estimated incidence of 1/3000 individuals. … [A193611] "The novel MEK 1/2 inhibitor, selumetinib, was initially approved solely for the treatment of pediatric patients with Neurofibromatosis type 1 (NF-1) and symptomatic, inoperable plexiform

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  8. Drug

    Naldemedine

    go.drugbank.com/drugs/DB11691
    ApprovedInvestigational

    It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier.

    Categories: Heterocyclic Compounds with 4 or More Rings
  9. Drug

    Tropisetron

    go.drugbank.com/drugs/DB11699
    ApprovedInvestigationalWithdrawn

    As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: NAVOBAN 5 MG 1 AMPUL, Navoban 5 mg - Kapseln
  10. Drug

    Amenamevir

    go.drugbank.com/drugs/DB11701
    Investigational

    Amenamevir has been used in trials studying the treatment of Herpes Zoster, Herpes Simplex, Herpes Genitalis, and Safety of Amenamevir.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers