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Displaying results 1581 - 1590 of 7452 in total
  1. Drug

    Rebamipide

    go.drugbank.com/drugs/DB11656
    ApprovedInvestigational

    Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.

    Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)
  2. Drug

    Eszopiclone

    go.drugbank.com/drugs/DB00402
    ApprovedInvestigational

    One major benefit of eszopiclone is that it is approved by the FDA for the long-term treatment of insomnia. … [A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity[A179827], offering a safer alternative to other drugs used for insomnia.

  3. Drug

    Rolitetracycline

    go.drugbank.com/drugs/DB01301
    ApprovedWithdrawn

    A pyrrolidinylmethyl tetracycline.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  4. Drug

    Obeticholic acid

    go.drugbank.com/drugs/DB05990
    ApprovedInvestigational

    [A192786] Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. … [L34650] Obeticholic acid is currently being considered for FDA approval to treat fibrosis caused by non-alcoholic liver steatohepatitis (NASH).

  5. Drug

    Carbopol 974P

    go.drugbank.com/drugs/DB05384
    ApprovedWithdrawn

    The compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but was discontinued.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    [A235850,A235855] A Cochrane review of patients being treated for primary hypertension shows that atenolol shows a risk ratio of 0.88 for cardiovascular disease risk and a risk ratio of 0.99 for mortality … Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize.

    Categories: Antihypertensive Agents Indicated for Hypertension
  7. Drug

    Trihexyphenidyl

    go.drugbank.com/drugs/DB00376
    ApprovedInvestigational

    [L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity. … Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced extrapyramidal disorders.

  8. Drug

    Didanosine

    go.drugbank.com/drugs/DB00900
    ApprovedInvestigational

    This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  9. Drug

    Tridihexethyl

    go.drugbank.com/drugs/DB00505
    ApprovedWithdrawn

    Tridihexethyl is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Tridihexethyl is an antimuscarinic, a...

    Categories: Drugs for Functional Gastrointestinal Disorders
  10. Drug

    Ipecac

    go.drugbank.com/drugs/DB13293
    ApprovedWithdrawn

    [L2753] Ipecac was approved by Health Canada as an OTC but all those products are now discontinued. … [L1113] The FDA does not have currently any approved product containing ipecac, however, ipecac as an ingredient is accepted to be sold over the counter in packages of 1 fluid ounce (30 ml) for the emergency