DB13293ApprovedWithdrawnSmall molecule
Ipecac is an emetic agent used to induce vomiting in poisoning. Ipecac is obtained from the plant Cephaelis ipecacuanha and contains a number of emetic alkaloids including emetine and cephaeline.
- Mechanism
- Curator reviewed · 2 references
The emetic components of ipecac, emetine and cephaeline, act centrally and locally in the gastrointestinal tract to cause vomiting. The mechanism by which ipecac performs his effect is by irritating the stomach lining and chemically stimulating the chemoreceptor trigger zone.
- Primary indication
- Ipecac is indicated as an emetic agent for the induction of vomiting in poisoning victims who ingested systemic poison in order to prevent absorption of the chemicals through the gastrointestinal tract.Curator reviewed · 8 structured indications
- First approval
- Canada, 1998
- Also known as
- Ipecac syrup · Ipecacuanha · Ipsatol
Resolves to
Clinical / RWD
What you can answer from here — as of January 17, 2025
Which other approved drugs treat the same conditions as Ipecac, and which companies have late-stage candidates in those indications?
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