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Benazeprilat

Quinaprilat

The active metabolite of the prodrug quinapril.

Temocapril

Temocapril is a prodrug-type angiotensin-I converting enzyme (ACE) inhibitor not approved for use in the United States, but is approved in Japan and South Korea. Temocapril can also be used in hemodialysis patients without risk of seriou...

Imidapril

Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.

Fosinoprilat

Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.

Sampatrilat

Sampatrilat is a small molecule drug. Sampatrilat has a monoisotopic molecular weight of 584.25 Da.

Telmisartan

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinit...

Sparsentan

Sparsentan is a dual antagonist of the endothelin type A receptor (ETAR) and the angiotensin II (Ang II) type 1 receptor (AT1R) with a similar affinity for both (9.3 nM for ETAR and 0.8 nM for AT1R). Sparsentan is first in its class and ...

Irbesartan

Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy. It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected t...

Delapril