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Simvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigationalSimvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk o...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: SIMVASTATIN Q-PH 10MG FTA, SIMVASTATIN Q-PH 20MG FTASphingolipid Signaling (Receptor)
smpdb.ca/view/SMP0524344SignalingThrough these receptor‑specific G protein couplings—spanning cAMP suppression, Ca²⁺ mobilization, PKC activation, Rho GTPase–driven cytoskeletal remodeling, and PI3K/Akt and MAPK pathways—S1P orchestrates
Enzymes: Sphingosine 1-phosphate receptor 2, Sphingosine 1-phosphate receptor 4TOL-101
go.drugbank.com/drugs/DB16980InvestigationalSynonyms: Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptorTrastuzumab duocarmazine
go.drugbank.com/drugs/DB16342InvestigationalTrastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).
Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens erbb2 (epidermal growth factor receptor 2, receptor tyrosineprotein kinase erbb-2, egfr2, her2, her-2, p185cerbb2, neu, cd340)), humanized monoclonal antibodyCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitorsPBCAR20A
go.drugbank.com/drugs/DB17189InvestigationalSynonyms: Allogeneic gene edited CD20-directed CAR (Chimeric Antigen Receptor) T cellsMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigationalMethotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate i...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: EMTHEXATE PF, EMTHEXATE PF 25 MG/MLPerindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalPerindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration....
Products: PERINDOPRIL ERB 1A PH 4MGTenofovir disoproxil
go.drugbank.com/drugs/DB00300ApprovedInvestigationalTenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug ...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: TENOFOVIRDISOPROXIL PU 245Becotatug
go.drugbank.com/drugs/DB19069InvestigationalJMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor
Synonyms: Jmt101 (fully human monoclonal igg1 antibody targeting epidermal growth factor receptor (egfr)), Immunoglobulin G1, anti-(human epidermal growth factor receptor) (human-Mus musculus monoclonal JMT101 γ1-chain), disulfide with human-Mus musculus monoclonal JMT101 κ-chain, dimerOctasulfur
go.drugbank.com/drugs/DB09353ApprovedSulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is...
Mixtures: Sulfatol SS, Se 10-5 SsProducts: Pharmassist Clarifex Ph Mud Crm 3.0%, Vichy Laboratoires Normaderm SOS Acne Rescue Spot Corrector