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Displaying results 151 - 160 of 32820 in total
  1. Drug

    Aluminum zirconium tetrachlorohydrex gly

    go.drugbank.com/drugs/DB11149
    ApprovedWithdrawn

    Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent.

    Mixtures: Ban Ultra Antiperspirant Roll-ONProducts: Lady Speed Stick 24/7, Arrid Xx Fresh Scent Solid 25%
  2. Drug

    Diphenhydramine

    go.drugbank.com/drugs/DB01075
    ApprovedInvestigational

    Diphenhydramine has also been shown to be implicated in a number of neurotransmitter systems that affect behaviour including dopamine, norepinephrine, serotonin, acetylcholine, and opioid [A1539]. … As a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties.

    Synonyms: 2-(benzhydryloxy)-N,N-dimethylethylamine, 2-diphenylmethoxy-N,N-demthylethanamineInternational brands: Dormarex 2
  3. Drug

    Treprostinil

    go.drugbank.com/drugs/DB00374
    ApprovedInvestigational

    However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room temperature. … [L41860] It is available in the following routes of administration: subcutaneous, intravenous, inhaled and oral. The first generic form of treprostinil became available in 2019.[A248775]

    Categories: Prostaglandins I, Cytochrome P-450 SubstratesProducts: REMODULIN 5 mg/ml Infusionslösung, Treposa 5 mg/ml Infusionslösung
  4. Drug

    Acetaminophen

    go.drugbank.com/drugs/DB00316
    ApprovedInvestigational

    [L5786,L5789,L4396] On September 22, 2025, the US FDA initiated a labeling change for acetaminophen products suggesting that the use of acetaminophen by pregnant women may be associated with an increased … FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent tablets, injection, suppository, and other forms.

    Synonyms: N-acetyl-p-aminophenol, 4-acetamidophenolInternational brands: Dapa X-S, Anacin-3
  5. Drug

    Desipramine

    go.drugbank.com/drugs/DB01151
    Approved

    In depressed individuals, desipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. … They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation.

    Synonyms: 5-(γ-methylaminopropyl)iminodibenzyl, 5-(gamma-methylaminopropyl)iminodibenzylCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor Antagonists
  6. Drug

    Omalizumab

    go.drugbank.com/drugs/DB00043
    ApprovedInvestigational

    [A39518] Omalizumab was first approved in the US in 2003 [A263507] and in Europe in 2005. … Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE).

    Synonyms: RHUMAB-E25Products: Xolair 75 mg/0.5 mL Solution for Injection in Pre-filled Syringe, XOLAİR 75 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET
  7. Drug

    Famciclovir

    go.drugbank.com/drugs/DB00426
    ApprovedInvestigational

    Famciclovir is a prodrug of penciclovir with higher oral bioavailability. … Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles).

    Synonyms: 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate, acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl esterCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Cefdinir

    go.drugbank.com/drugs/DB00535
    ApprovedInvestigational

    Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie. … It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin.

    Synonyms: (6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino}-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acidInternational brands: Omnicef R
  9. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. … [A204155] Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and continue to grow in popularity, falling behind only ACE inhibitors in terms of prescription

    Mixtures: Triplixam 5 mg/1,25 mg/5 mg Filmtabletten, Triplixam 10 mg/2,5 mg/5 mg FilmtablettenCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 Substrates
  10. Target

    NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

    go.drugbank.com/bio_entities/BE0000493
    TargetHumans

    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30879903, PubMed:3155...

    Polypeptides: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial