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Displaying results 151 - 160 of 10000 in total
  1. Drug

    Afamitresgene autoleucel

    go.drugbank.com/drugs/DB18592
    ApprovedInvestigational

    [L51114] On August 2, 2024, the FDA granted the accelerated approval of afamitresgene autoleucel, making it the first FDA-approved TCR gene therapy and the first gene therapy for the treatment of synovial … self-inactivating lentiviral vector (LV) expressing an affinity-enhanced T cell receptor (TCR) specific for the human MAGE-A4.

    Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE, HUMAN MELANOMA ANTIGEN A4 (MAGE FAMILY MEMBER A4, A
  2. Drug

    Inodiftagene vixteplasmid

    go.drugbank.com/drugs/DB16017
    Investigational

    Inodiftagene vixteplasmid is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of the promoter region of the human H19 gene (an imprinted maternally expressed … non-protein coding gene).

    Synonyms: Dna Plasmid Expressing Diphtheria Toxin Triggered By The Presence Of Oncofetal Gene H19, dT-A-H19
  3. Drug

    Isopropyl alcohol

    go.drugbank.com/drugs/DB02325
    ApprovedInvestigational

    An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.

    Synonyms: 2-PropanolMixtures: Superiorwor hand sanitizer with green apple, Superiorwor hand sanitizer with green apple
  4. Drug

    ALLO-715

    go.drugbank.com/drugs/DB18640
    Investigational

    ALLO-715 is an allogeneic chimeric antigen receptor T Cell therapy targeting B cell maturation antigen (BCMA).

    Synonyms: Allogenic Chimeric Antigen Receptor T Cells Targeting B Cell Maturation Antigen (BCMA)
  5. Drug

    AGIL-FA

    go.drugbank.com/drugs/DB16973
    Experimental

    Synonyms: Recombinant adeno-associated viral vector serotype 5 carrying the gene for the human frataxin protein
  6. Drug

    Allantoin

    go.drugbank.com/drugs/DB11100
    ApprovedInvestigational

    In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. … Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label].

    Synonyms: N-(2,5-Dioxo-4-imidazolidinyl)urea, 5-UreidohydantoinMixtures: Hands First 4 in 1, Botaneth Pronoxin Hair Regainer Fs2 Activator 2-A 2-B
  7. Drug

    Antihemophilic factor, human recombinant

    go.drugbank.com/drugs/DB00025
    ApprovedInvestigational

    Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells

    International brands: Monarc-MMixtures: HAEMATE P, HAEMATE P
  8. Drug

    AD-114

    go.drugbank.com/drugs/DB18285
    Experimental

    Synonyms: Human single domain antibody-like protein inhibitor of the chemokine receptor type 4
  9. Drug

    Drozitumab

    go.drugbank.com/drugs/DB19106
    Investigational

    Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), a member of tumor necrosis factor related apoptosis-inducing ligand (TRAIL) … It was developed by Genentech as a drug for the treatment of cancers

    Synonyms: Immunoglobulin g1, anti-(human citokine receptor dr5 (death receptor 5)) (human monoclonal heavy chain), disulfide with human l3-chain, dimer
  10. Drug

    RAD 502

    go.drugbank.com/drugs/DB17328
    Experimental

    Synonyms: Lutetium-177 labeled humanized monoclonal antibody targeting leucine rich repeat containing 15 (LRRC15)