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Aliskiren
go.drugbank.com/drugs/DB09026ApprovedInvestigational[A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007.
BNT162B2 Omicron (LP.8.1)
go.drugbank.com/drugs/DB23337Approved[L53723] The 2025-2026 formulation of Pfizer-BioNTech's Comirnaty was approved by the US FDA in August 2025.[L53728]
Pantoprazole
go.drugbank.com/drugs/DB00213ApprovedInvestigational[FDA Label] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.
Products: Nra-pantoprazoleBudesonide
go.drugbank.com/drugs/DB01222ApprovedInvestigational[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598] It is also available in a combination product with [formoterol].[L10619]
Categories: Corticosteroid Hormone Receptor AgonistsGemfibrozil
go.drugbank.com/drugs/DB01241ApprovedInvestigational[L8525] Gemfibrozil was granted FDA approval on 21 December 1981.[L8525]
Categories: Peroxisome Proliferator Receptor alpha Agonist, Peroxisome Proliferator-activated Receptor alpha AgonistsSulfathiazole
go.drugbank.com/drugs/DB06147ApprovedVet approvedWithdrawnExcept for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products containing sulfathiazole.[L43942]
Fospropofol
go.drugbank.com/drugs/DB06716ApprovedIllicitInvestigationalWithdrawnFDA approved in December 2008. Fospropofol is a Schedule IV controlled substance in the United States under the Controlled Substances Act.
Etripamil
go.drugbank.com/drugs/DB12605ApprovedInvestigational[A275243, A275248] The nasal formulation of etripamil was first approved by the FDA on December 12, 2025 for the conversion of acute symptomatic episodes of paroxysmal supraventricular tachycardia (PSVT
Tegafur-uracil
go.drugbank.com/drugs/DB09327Approved[A32073] It is approved in different countries but it is not yet approved by the FDA, Health Canada or EMA.