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Indium In-111 chloride
go.drugbank.com/drugs/DB09490ApprovedIt is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in O.04M HCI. … Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint (satumomab pendetide) or ProstaScint (capromab pendetide) used for _in vivo_ diagnostic imaging procedures
Bremelanotide
go.drugbank.com/drugs/DB11653ApprovedBremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women.[L9635] Bremelanotide does not interact with alcohol. … [A179686] The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown.
Categories: Receptor, Melanocortin, Type 3, agonists, Receptor, Melanocortin, Type 4, agonistsMetharbital
go.drugbank.com/drugs/DB00463ApprovedWithdrawnMetharbital is a barbiturate anticonvulsant, similar to phenobarbital, marketed as Gemonil by Abbott Laboratories. It was patented in 1905 by Emil Fischer of Merck.
Categories: Heterocyclic Compounds, 1-RingEszopiclone
go.drugbank.com/drugs/DB00402ApprovedInvestigationalEszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia. … One major benefit of eszopiclone is that it is approved by the FDA for the long-term treatment of insomnia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (S)-Zopiclone, (S)-6-(5-Chloro-2-pyridinyl)- 7-oxo- 6,7-dihydro- 5H-pyrrolo[3,4-b]pyrazin-5-yl- 4-methyl- 1-piperazinecarboxylateTropicamide
go.drugbank.com/drugs/DB00809ApprovedTropicamide is an alkaloid atropine‐derived anticholinergic drug and a non‐selective antagonist of muscarinic acetylcholine (mACh) receptors. … [A229958] It is also used in combination with [hydroxyamphetamine] for the same indication.
Mixtures: T-P OFTENO, T-P OFTENOCategories: Heterocyclic Compounds, 1-RingEmapalumab
go.drugbank.com/drugs/DB14724ApprovedInvestigationalEmapalumab, also known as NI-0501, is a fully human monoclonal antibody that targets interferon gamma. … Emapalumab development was sponsored by NovImmune SA, further developed by Sobi and FDA approved on November 20, 2018.
Droxicam
go.drugbank.com/drugs/DB09215ApprovedWithdrawnDroxicam is an oxicam non-steroidal anti-inflammatory drug and a prodrug of [DB00554]. … It is used to reduce pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingCollagenase clostridium histolyticum
go.drugbank.com/drugs/DB00048ApprovedInvestigational[L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA for the treatment of cellulite in adult women. … Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum.
Synonyms: Clostridiopeptidase ARisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] It is one of the most widely used SGAs. [Paliperidone], another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). … Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesInternational brands: Risperidal M-TabSulfadoxine
go.drugbank.com/drugs/DB01299ApprovedInvestigationalWithdrawnA long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.
Synonyms: 4-Sulfanilamido-5,6-dimethoxypyrimidine