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Displaying results 1591 - 1600 of 10000 in total
  1. Drug

    Bioymifi

    go.drugbank.com/drugs/DB17493
    Experimental

    Bioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL) mimetic. … Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through a caspase-dependent pathway. Bioymifi is currently being investigated as an anti-tumor agent.

    Synonyms: 5-(5-((3-(4-bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione, 5-[5-[(Z)-[3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]isoindole-1,3-dioneCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Disoxaril

    go.drugbank.com/drugs/DB08726
    Experimental

    5-(7-(4-(4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole is a solid. This compound belongs to the phenol ethers. … Known drug targets of 5-(7-(4-(4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole include genome polyprotein.

    Synonyms: 5-(7-(4-(4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole, ISOXAZOLE, 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL-Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    trans-urocanic acid

    go.drugbank.com/drugs/DB01971
    Experimental

    Synonyms: (E)-3-(1H-imidazol-4-yl)-2-propenoic acid, (2E)-3-(1H-imidazol-4-yl)acrylic acidCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Aminopterin

    go.drugbank.com/drugs/DB08878
    ApprovedWithdrawn

    In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment of psoriasis.

    Synonyms: 4-amino-4-deoxypteroylglutamate, 4-amino-PGACategories: Heterocyclic Compounds, 2-Ring
  5. Drug

    [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE

    go.drugbank.com/drugs/DB08423
    Experimental

    Synonyms: [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE
  6. Drug

    Paromomycin

    go.drugbank.com/drugs/DB01421
    ApprovedInvestigational

    An oligosaccharide antibiotic produced by various streptomyces. [PubChem]

    Synonyms: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside, Neomycin EProducts: GABROSIDIN 0.5 G ENJEKTABL FLAKON, 1 ADET
  7. Drug

    4-Carboxy-4-Aminobutanal

    go.drugbank.com/drugs/DB04388
    Experimental

    Synonyms: 4-Carboxy-4-Aminobutanal
  8. Drug

    4-PIPERIDIN-4-YLBUTANAL

    go.drugbank.com/drugs/DB04654
    Experimental

    Synonyms: 4-PIPERIDIN-4-YLBUTANAL
  9. Drug

    NP-10679

    go.drugbank.com/drugs/DB18040
    Investigational

    Synonyms: (R)-6-(2-hydroxy-3-(4-(4-(trifluoromethyl)phenyl)piperazin- 1-yl)propoxy)-3,4-dihydroquinolin-2(1H)-one
  10. Drug

    Avotaciclib

    go.drugbank.com/drugs/DB16652
    Investigational

    Avotaciclib is under investigation in clinical trial NCT03579836 (Evaluation of Safety and Efficacy in BEY1107 in Monotherapy Gemcitabine Combination in Patient With Pancreatic Cancer).

    Synonyms: 2,6-bis(2-aminopyrimidin-4-yl)pyridin-3-ol