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Displaying results 1601 - 1610 of 1993 in total
  1. Drug

    Casimersen

    go.drugbank.com/drugs/DB14984
    ApprovedInvestigational

    [A218186] Casimersen is the most recent in a line of approved PMOs for treating DMD, including [eteplirsen] and [viltolarsen].

  2. Drug

    Pemigatinib

    go.drugbank.com/drugs/DB15102
    ApprovedInvestigational

    With increasing research on the pathogenesis of cholangiocarcinoma and potential therapeutic targets for anticancer drug treatment, recent studies show that up to 45% of patients with intrahepatic cholangiocarcinoma … It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells.

    Categories: Fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitors, Receptor, Fibroblast Growth Factor, Type 1, antagonists & inhibitors
  3. Drug

    Deferitazole

    go.drugbank.com/drugs/DB13120
    Investigational

    It has been used in trials studying the treatment and basic science of Beta-thalassemia, Hepatic Impairment, Impaired Renal Function, Transfusional Iron Overload, and Iron Overload Due to Repeated Red

  4. Drug

    Quercus rubra pollen

    go.drugbank.com/drugs/DB10481
    Approved

    Quercus rubra pollen is the pollen of the Quercus rubra plant. Quercus rubra pollen is mainly used in allergenic testing.

    Mixtures: 2-oak Mix, Red/white Pollen, 5-oak Mix, Blackjack/bur/post/red/white PollenProducts: Red Oak, Northern Red Oak
  5. Target

    NADP-dependent malic enzyme

    go.drugbank.com/bio_entities/BE0000604
    TargetHumans

    Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate

    Synonyms: NADP-ME
  6. Drug

    Alpelisib

    go.drugbank.com/drugs/DB12015
    ApprovedInvestigational

    [A179209] Approved by the FDA in May 2019, alpelisib is the first approved PI3K inhibitor indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-

  7. Drug

    Light mineral oil

    go.drugbank.com/drugs/DB11579
    Approved

    Mixtures: retaine MGD
  8. Indication

    Diabetes Mellitus, Insulin Dependent

    go.drugbank.com/conditions/DBCOND0035532
    Drugs: Insulin pork
    Synonyms: Insulin dependent diabetes mel
  9. Drug

    Ferric derisomaltose

    go.drugbank.com/drugs/DB15617
    ApprovedInvestigational

    Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells.

  10. Drug

    Naphazoline

    go.drugbank.com/drugs/DB06711
    Approved

    Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles . It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations . Naphazoline was firs...

    Mixtures: Rhino Mex, Red Eye ReliefCategories: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-2 Receptor Agonists