Insulin pork is a purified form of porcine insulin used to control hyperglycemia in diabetes mellitus. Insulin isolated from pig pancreas.
- Mechanism
- Curator reviewed
Insulin binds to the insulin receptor (IR), a heterotetrameric protein consisting of two extracellular alpha units and two transmembrane beta units. The binding of insulin to the alpha subunit of IR stimulates the tyrosine kinase activity intrinsic to the beta subunit of the receptor. The bound receptor is able to autophosphorylate and phosphorylate numerous intracellular substrates such as insulin receptor substrates (IRS) proteins, Cbl, APS, Shc and Gab 1. These activated proteins, in turn, lead to the activation of downstream signaling molecules including PI3 kinase and Akt. Akt regulates the activity of glucose transporter 4 (GLUT4) and protein kinase C (PKC) which play a critical role in metabolism.
- Primary indication
- For the treatment of type I and II diabetes mellitus.Curator reviewed · 2 structured indications
- Formula / weight
- C257H387N65O76S6 · 5795.6 Da
- First approval
- Canada, 1980
- Also known as
- Insulin (pork) · Insulin porcine · Insulin purified porcine · Insulin purified pork · Insulin, porcine
- Brand names
Resolves to
What you can answer from here — as of July 17, 2026
Which drugs share a target with Insulin pork, and which of those have an active Phase 3 trial?
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