Search
Nilvadipine
go.drugbank.com/drugs/DB06712ApprovedNilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
Sonrotoclax
go.drugbank.com/drugs/DB18753ApprovedInvestigationalIt is the first BCL-2 inhibitor approved for MCL and the second oncology-approved BCL-2 inhibitor overall, following venetoclax. … [A275521,A275522] On May 13, 2026, the FDA granted accelerated approval to sonrotoclax for the treatment of adult patients with relapsed or refractory mantle cell lymphoma (MCL) after at least two prior
Difamilast
go.drugbank.com/drugs/DB14987ApprovedInvestigationalThe drug is indicated for the topical treatment of mild to moderate atopic dermatitis in adults and pediatric patients 2 years of age and older [L55042]. It is approved in Japan and the United States.
Hyaluronidase (ovine)
go.drugbank.com/drugs/DB00070ApprovedHighly purified sheep hyaluronidase for administration by injection into the vitreous of the eye.
Benznidazole
go.drugbank.com/drugs/DB11989ApprovedInvestigational[L939] It is the first treatment made available in the United States for Chagas disease. … Benznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.
Rimonabant
go.drugbank.com/drugs/DB06155ApprovedWithdrawnIt was rejected for approval for use in the United States. … It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite.
Etravirine
go.drugbank.com/drugs/DB06414ApprovedInvestigationalEtraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection. … On March 26, 2012, approval was extended for use in treatment-experienced pediatric patients 6 to 18 years of age, weighing at least 16 kg.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseIdelalisib
go.drugbank.com/drugs/DB09054ApprovedInvestigationalFor the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab alone would be considered appropriate therapy due to other … In contrast to the other class IA PI3Ks p110α and p110β, p110δ is principally expressed in leukocytes (white blood cells) and is important for the function of T cells, B cell, mast cells and neutrophils
Diazoxide
go.drugbank.com/drugs/DB01119ApprovedInvestigationalFDA-approved therapy for this condition. … [A255647,L44612] In March 2025, an extended-release formulation of diazoxide choline was approved by the FDA for the treatment of hyperphagia in patients with Prader-Willi syndrome, becoming the first
Papaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalIt is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation.
Categories: Drugs for Functional Gastrointestinal Disorders