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Displaying results 1611 - 1620 of 10000 in total
  1. Drug

    Phycomyces blakesleeanus

    go.drugbank.com/drugs/DB10845
    Approved

    Phycomyces blakesleeanus is a fungus which can provoke allergic reactions. Phycomyces blakesleeanus extract is used in allergenic testing.

    Mixtures: Treatment Set TS128871
  2. Drug

    Sporotrichum pruinosum

    go.drugbank.com/drugs/DB10846
    Approved

    Sporotrichum pruinosum is a fungus which can provoke allergic reactions. Sporotrichum pruinosum extract is used in allergenic testing.

    Mixtures: Treatment Set TS128871
  3. Drug

    Stachybotrys chartarum

    go.drugbank.com/drugs/DB10847
    Approved

    Stachybotrys chartarum is a fungus which can provoke allergic reactions. Stachybotrys chartarum extract is used in allergenic testing.

    Mixtures: Treatment Set TS128871
  4. Drug

    Syncephalastrum racemosum

    go.drugbank.com/drugs/DB10848
    Approved

    Syncephalastrum racemosum is a fungus which can provoke allergic reactions. Syncephalastrum racemosum extract is used in allergenic testing.

    Mixtures: Treatment Set TS128871
  5. Drug

    Golimumab

    go.drugbank.com/drugs/DB06674
    ApprovedInvestigational

    Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate … In the U.S. and Canada, golimumab is marketed under the brand name Simponi®. The FDA label includes a black box warning of serious infections and malignancy.

  6. Drug

    Moxetumomab pasudotox

    go.drugbank.com/drugs/DB12688
    ApprovedInvestigational

    CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma. … [A38864] MxP appears as an improved form of BL22 by the mutation of the Fv region and the antibody phage-displayed. As well the residues SSY in the heavy chain are mutated to THW.

  7. Drug

    Bedaquiline

    go.drugbank.com/drugs/DB08903
    ApprovedInvestigational

    Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. … The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity.

    Categories: Antiinfectives for Systemic Use
  8. Drug

    Guanfacine

    go.drugbank.com/drugs/DB01018
    ApprovedInvestigational

    Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release

  9. Target

    DNA-dependent protein kinase catalytic subunit

    go.drugbank.com/bio_entities/BE0002385
    TargetHumans

    Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune … Phosphorylates 'Ser-139' of histone variant H2AX, thereby regulating DNA damage response mechanism (PubMed:14627815, PubMed:16046194).

    Synonyms: Ser-473 kinase
  10. Drug

    Clorazepic acid

    go.drugbank.com/drugs/DB00628
    ApprovedIllicit

    Also, the use of clorazepate exposes users to users to the risks of abuse, misuse, and addiction, and its continued use may lead to significant physical dependence. … [A256683,T883] The concomitant use of clorazepate and opioids may result in profound sedation, respiratory depression, coma, and death.