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Displaying results 1611 - 1620 of 10000 in total
  1. Drug

    Antihemophilic factor human

    go.drugbank.com/drugs/DB13192
    ApprovedInvestigational

    Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of … Congenital loss or deficiency of Factor VIII results in the physiologic impairment of the coagulation clotting cascade, and as a result, leads to easy bruising and bleeding.

    Mixtures: BIOSTATE FOR INJECTION 50 iu/ml, BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICICategories: Hemophilia A, Blood and Blood Forming Organs
  2. Drug

    Navafenterol

    go.drugbank.com/drugs/DB19195
    Investigational

    Navafenterol is under investigation in clinical trial NCT02971293 (Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: -hydroxy-.alpha.-2-thienyl-, trans-4-((3-(5-((((2r)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-hydroxyethyl)amino)methyl)-1h-benzotriazol-1-yl)propyl)methylamino)cyclohexyl ester, Trans-4-((3-(5-((((2r)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro-5- quinolinyl)ethyl)amino)methyl)-1h-benzotriazol-1-yl)propyl)(methyl)amino)cyclohexyl hydroxy(di-2-thienyl)acetate
  3. Drug

    Azimilide

    go.drugbank.com/drugs/DB04957
    Investigational

    Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels.

    Categories: Heterocyclic Compounds, 1-Ring, Calcium-Regulating Hormones and AgentsSynonyms: 1-((5-(P-CHLOROPHENYL)FURFURYLIDENE)AMINO)-3-(4-(4-METHYL-1-PIPERAZINYL)BUTYL)HYDANTOIN, 2,4-IMIDAZOLIDINEDIONE, 1-(((5-(4-CHLOROPHENYL)-2-FURANYL)METHYLENE)AMINO)-3-(4-(4-METHYL-1-PIPERAZINYL)BUTYL)-
  4. Drug

    Bromopride

    go.drugbank.com/drugs/DB09018
    Investigational

    Bromopride is a dopamine antagonist used as an antiemetic. Its prokinetic properties are similar to those of metoclopramide. It is unavailable in America or the United Kingdom.

    Mixtures: ENZYMED®TABLETAS RECUBIERTASCategories: Alimentary Tract and Metabolism, Benzamides and benzamide derivatives
  5. Drug

    NUC-7738

    go.drugbank.com/drugs/DB19148
    Investigational

    NUC-7738 is under investigation in clinical trial NCT03829254 (A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma).

    Categories: Heterocyclic Compounds, 2-RingSynonyms: L-Alanine, N-(3′-deoxy-P-phenyl-5′-adenylyl)-, phenylmethyl ester (ACI)
  6. Drug

    PRX-08066

    go.drugbank.com/drugs/DB05607
    Investigational

    Synonyms: 5-((4-(6-CHLOROTHIENO(2,3-D)PYRIMIDINE-4-YLAMINO)PIPERIDIN-1-YL)METHYL)-2-FLUOROBENZONITRILE MONOFUMURATE, 5-((4-(6-chlorothieno[2,3-d]pyrimidine-4-ylamino)piperidin-1-yl)methyl)-2-fluorobenzonitrile monofumurateCategories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor Antagonists
  7. Drug

    EHP-102

    go.drugbank.com/drugs/DB16933
    Experimental

    Synonyms: 2-((2e)-3,7-dimethyl-2,6-octadien-1-yl)-6-(ethylamino)-3-hydroxy-5-pentyl-2,5-cyclohexadiene-1,4-dione, 2,5-cyclohexadiene-1,4-dione, 2-((2e)-3,7-dimethyl-2,6-octadien-1-yl)-6-(ethylamino)-3-hydroxy-5-pentyl-
  8. Drug

    5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole

    go.drugbank.com/drugs/DB08728
    Experimental

    5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole is a solid. This compound belongs to the phenol ethers. … Known drug targets of 5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole include genome polyprotein.

    Synonyms: 5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole
  9. Drug

    Spebrutinib

    go.drugbank.com/drugs/DB11764
    Investigational

    Spebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(5-FLUORO-2-(4-(2-METHOXYETHOXY)PHENYLAMINO)PYRIMIDIN-4-YLAMINO)PHENYL)ACRYLAMIDE, N-(3-(5-fluoro-2-(4-(2-methoxyethoxy)phenylamino)pyrimidin-4-ylamino)phenyl)acrylamide
  10. Drug

    (1R,2S)-2-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)cyclohexanecarboxylic acid

    go.drugbank.com/drugs/DB07850
    Experimental

    Synonyms: (1R,2S)-2-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)cyclohexanecarboxylic acid