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Procaine benzylpenicillin
go.drugbank.com/drugs/DB09320ApprovedVet approvedBenzylpenicillin is active against a wide range of organisms and is the drug of first choice for many infections. … It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts.
Synonyms: Penicillin G procaineCategories: combinations of penicillins, Penicillin GNadolol
go.drugbank.com/drugs/DB01203ApprovedInvestigationaloffer better rates of adverse effects. … [A34177] Nadolol was granted FDA approval on 10 December 1979.[L7922]
Mixtures: CORGARETIC (NADOLOL/ BENDROFLUMETIAZIDA) 80/5 MGProducts: NADOLOL MK 80 MG TABLETAS, CORGARD (NADOLOL) 80 MG TABLETASNaldemedine
go.drugbank.com/drugs/DB11691ApprovedInvestigationalNaldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation. … It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier.
Categories: Heterocyclic Compounds with 4 or More RingsSibutramine
go.drugbank.com/drugs/DB01105ApprovedIllicitWithdrawnIn October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease. … Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity.
Categories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: SINHABIT 10 MG, SINHABIT 15 MGPivmecillinam
go.drugbank.com/drugs/DB01605ApprovedInvestigationalPivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa.
Categories: combinations of penicillinsProducts: Selexid 200 mg Filmtabletten, Selexid 400 mg film-coated tabletsLonapegsomatropin
go.drugbank.com/drugs/DB16220ApprovedInvestigationalLonapegsomatropin, also known as TransCon hGH or ACP 001, is a methoxypegylated prodrug of human growth hormone ([somatropin]) indicated for the treatment of children 1 year and older, weighing at least … [L36380,L10971] Lonapegsomatropin was granted FDA approval on 25 August 2021.[L36380] It was later approved by the European Commission on 13 January 2022.[L39900]
Pegulicianine
go.drugbank.com/drugs/DB18731ApprovedInvestigationalIt is used following surgical resection of the primary tumor to detect areas of remaining cancer. … Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence quencher that keeps the parent molecule optically inactive.
Categories: Compounds used in a research, industrial, or household settingBelzutifan
go.drugbank.com/drugs/DB15463ApprovedInvestigationalor stop the growth of VHL-associated tumors. … Belzutifan received FDA approval for the treatment of select VHL-associated cancers on August 13, 2021.
Tividenofusp alfa
go.drugbank.com/drugs/DB17628ApprovedInvestigationalThis milestone made it the first drug specifically approved to treat the neurologic manifestations of Hunter syndrome [L56099]. … Developed by Denali Therapeutics, tividenofusp alfa received FDA approval on March 25, 2026, under the accelerated approval pathway [L56097, L56099].
Florquinitau (18F)
go.drugbank.com/drugs/DB19215Approved[L64052] It binds to aggregated tau protein, which in Alzheimer's disease forms the neurofibrillary tangles (NFTs) that are one of the two components required for a neuropathological diagnosis of the disease … [L64052] Florquinitau F 18, also known as MK-6240, was approved by the FDA on August 14, 2026 for PET of the brain in adults with cognitive impairment who are being evaluated for Alzheimer's disease
Categories: Diagnostic Uses of Chemicals