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Lefamulin
go.drugbank.com/drugs/DB12825ApprovedLefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia. A pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus. Lefamulin is av...
Ketazolam
go.drugbank.com/drugs/DB01587ApprovedWithdrawnKetazolam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. Ketazolam is not approved in Canada or America.
Pegcetacoplan
go.drugbank.com/drugs/DB16694ApprovedInvestigationalPegcetacoplan is a complement inhibitor indicated in the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Prior to its FDA approval, patients with PNH were typically treated with the C5 inhibiting monoclonal antibody eculizumab. P...
Denosumab
go.drugbank.com/drugs/DB06643ApprovedInvestigationalIt is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. … [A263071] Chemically, it consists of 2 heavy and 2 light chains, with each light chain consisting of 215 amino acids and each heavy chain consisting of 448 amino acids with 4 intramolecular disulfides.
Diazoxide
go.drugbank.com/drugs/DB01119ApprovedInvestigational[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity.
Nelfinavir
go.drugbank.com/drugs/DB00220ApprovedInvestigationalIt is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.
Growth/differentiation factor 15
go.drugbank.com/bio_entities/BE0010537TargetHumansHormone produced in response to various stresses to confer information about those stresses to the brain, and trigger an aversive response, characterized by nausea, vomiting, and/or loss of appetite (PubMed:23468844, PubMed:24971956, Pub...
Synonyms: MIC-1Ubenimex
go.drugbank.com/drugs/DB03424InvestigationalIt is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.
BNT162B2 Omicron (LP.8.1)
go.drugbank.com/drugs/DB23337Approved[L53723] It encodes the spike protein from the Omicron LP.8.1 subvariant of SARS-CoV-2.[L53723] The 2025-2026 formulation of Pfizer-BioNTech's Comirnaty was approved by the US FDA in August 2025.
Povidone
go.drugbank.com/drugs/DB11061ApprovedInvestigationalWithdrawnIt is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. … The clinical effectiveness of [DB06812] on wound healing remains somewhat controversial, as it was demonstrated in a few clinical studies that the application of the compound in wounds was associated with
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