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Regdanvimab
go.drugbank.com/drugs/DB16405ApprovedWithdrawnTrials investigating the use of regdanvimab as a therapeutic candidate for the treatment of COVID-19 began in mid-2020. … Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of the SARS-CoV-2 spike protein.
Panitumumab
go.drugbank.com/drugs/DB01269ApprovedInvestigationalPanitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent.
Synonyms: ABX-EGFGluconolactone
go.drugbank.com/drugs/DB04564ApprovedGluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid. … Pure gluconolactone is a white odorless crystalline powder.
Deucravacitinib
go.drugbank.com/drugs/DB16650ApprovedInvestigational[A246938, A246943] This selectivity towards TYK2 may lead to an improved safety profile of deucravacitinib, as nonselective JAK inhibitors are associated with a range of adverse effects such as altered … Deucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor.
Activated charcoal
go.drugbank.com/drugs/DB09278ApprovedInvestigationalIt is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances … It works by binding to the poison in the gastric contents in a reversible fashion thus may be adminstered together with a cathartic to reduce the small intestine transit time.
Categories: Compounds used in a research, industrial, or household settingProducts: W Lab Sebum Out Peel Off PackDextropropoxyphene
go.drugbank.com/drugs/DB00647ApprovedIllicitWithdrawnThe levo-isomer appears to exhibit a very limited antitussive effect. … The drug is often referred to as the general form, "propoxyphene", however only the dextro-isomer (dextropropoxyphene) has any analgesic effect.
Mixtures: 692 TabProducts: 642 TabIvermectin
go.drugbank.com/drugs/DB00602ApprovedInvestigationalVet approved(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A<sub>1a</sub> (22,23-dihydroavermectin B<sub>1b</sub>). … [L31453] Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A<sub>1a</sub> (22,23-dihydroavermectin B<sub>1a</sub>) and 10% 5-O-demethyl-25-de
Categories: Compounds used in a research, industrial, or household settingIsoflurophate
go.drugbank.com/drugs/DB00677ApprovedWithdrawnAn irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma.
Diamorphine
go.drugbank.com/drugs/DB01452ApprovedIllicitDiamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. … As heroin, it is illegal to manufacture, possess, or sell in the United States and the UK. However, under the name diamorphine, heroin is a legal prescription drug in the United Kingdom.
Gimeracil
go.drugbank.com/drugs/DB09257ApprovedInvestigationalThe main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug that acts on rapidly dividing cancer cells. … This allows higher concentrations of 5-FU to be achieved with a lower dose of tegafur, thereby also reducing toxic side effects.