Gluconolactone

DB04564ApprovedSmall moleculeCalculi Dissolution Agent

Gluconolactone is a polyhydroxy acid used in the dissolution of calculi and used as an additive in various drug products to maintain consistency and other characteristics. Gluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent.

Chemical structure of Gluconolactone
Formula / weight
C6H10O6 · 178.14 g/mol (avg)
First approval
United States, 1991
Also known as
1,5-D-gluconolactone · 1,5-Gluconolactone · delta-gluconolactone · Gluconic acid lactone · Glucono delta-lactone
Code names
E-575 · INS-575 · INS NO.575 · NSC-34393
Brand names
  • Renacidin

Resolves to

Compound
UNIIWQ29KQ9POTCAS90-80-2ChEMBLCHEMBL1200829ChEBI16217PubChem7027KEGGD04332
Clinical / RWD
RxNorm25842
Structure
InChIKeyPHOQVHQSTUBQQK-SQOUGZDYSA-NSMILESOC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O
Targets
P09848LCT

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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1Clinical trialPhase, status and sponsor resolved per trial
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3Structured indicationsCondition, population, route and combination as fields, not prose
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2Marketed productsAcross 1 country and 1 labeller
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1+ReferenceStructured and connected to the statements they support
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