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Displaying results 1631 - 1640 of 10000 in total
  1. Drug

    Lesinurad

    go.drugbank.com/drugs/DB11560
    ApprovedWithdrawn

    Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. … It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with

    Products: ZURAMPIC® COMPRIMIDOS RECUBIERTOS CON PELICULA
  2. Drug

    Ferrous fumarate

    go.drugbank.com/drugs/DB14491
    ApprovedInvestigational

    Used in treatment of iron deficiency anemia.

    Mixtures: Prenatal Vitamin-mineral Supplement Folic 5mg, Pnv-VP-UCategories: Diet, Food, and Nutrition, Blood and Blood Forming Organs
  3. Drug

    Procyclidine

    go.drugbank.com/drugs/DB00387
    ApprovedInvestigational

    A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.

    Products: Procyclid Tab 5mg, Kemadrin Tab 5mg
  4. Drug

    Pitavastatin

    go.drugbank.com/drugs/DB08860
    ApprovedInvestigational

    [A181409,A181535,A181538,A1793] Study data has confirmed that pitavastatin's potency in lowering LDL-C is comparable to that of other statins but also has increased efficacy in increasing HDL-C (also known … [A181084] Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an important risk factor for the development of CVD.

    Categories: pitavastatin and ezetimibeProducts: LIVAZO 2MG FTA, LIVALO FILM-COATED TABLETS 2MG
  5. Drug

    Gemfibrozil

    go.drugbank.com/drugs/DB01241
    ApprovedInvestigational

    [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias.

    Categories: Drug-Related Side Effects and Adverse Reactions, Metabolic Side Effects of Drugs and SubstancesProducts: Lopid Cap 300mg, Gemfibrozil Cap 300mg
  6. Drug

    Eculizumab

    go.drugbank.com/drugs/DB01257
    ApprovedInvestigational

    [L6919] In Q1 2023, the EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion of two formulations of eculizumab indicated for the treatment of paroxysmal nocturnal hemoglobinuria … Eculizumab is a monoclonal antibody that targets complement protein C5.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: ELIZARIA® 10MG/ML SOLUCIÓN CONCENTRADA PARA INFUSIÓN, Soliris 10mg/ml Concentrate for Solution for Infusion
  7. Drug

    Capsicum

    go.drugbank.com/drugs/DB10897
    Approved

    Capsicum (Chili pepper) allergenic extract is used in allergenic testing.

    Mixtures: Zaxs Aches and Pain, Odynia-UProducts: SinolM Fast Allergy and Sinus Relief All-Natural Nasal
  8. Drug

    Ulipristal

    go.drugbank.com/drugs/DB08867
    ApprovedInvestigational

    Nevertheless, current and ongoing research into the agent's mechanism of action as an emergency contraceptive continue to provide potentially plausible evidence that ulipristal may, in fact, elicit activity … The exact mechanism of action for ulipristal is still currently debated, though there is evidence that it functions by inhibiting ovulation.

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemProducts: ESMYA TABLET 5MG, Esmya 5mg Tablets
  9. Drug

    Enfortumab vedotin

    go.drugbank.com/drugs/DB13007
    ApprovedInvestigational

    Enfortumab vedotin is an antibody-drug conjugate used in the treatment of patients with advanced, treatment-resistant urothelial cancers. … The clinical development of enfortumab vedotin was the result of a collaboration between Astellas Pharma and Seattle Genetics [A188868] and it was first approved for use in the United States in December

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Padcev 20mg Powder for Concentrate for Solution for Infusion, Padcev 30mg Powder for Concentrate for Solution for Infusion
  10. Drug

    Maraviroc

    go.drugbank.com/drugs/DB04835
    ApprovedInvestigational

    It was originally labelled as UK-427857 during development but was assigned the Maraviroc name as it entered trials. It was approved for use by the FDA in August, 2007. … interaction between HIV and CCR5.

    Products: Celsentri Film-Coated Tablet 150mg, Celsentri Film-Coated Tablet 300mg