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Dequalinium
go.drugbank.com/drugs/DB04209Approved[A249255] It is a quaternary ammonium compound,[L42190] as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. … [A249255] First used as an antiseptic and disinfectant in the 1950s, dequalinium is still found in various OTC products to treat conditions of oral infections and inflammation.
Synonyms: 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride, Decamethylenebis(4-aminoquinaldinium chloride)Mixtures: EFISOL-C, JASIMENTH C PASTILLESBicalutamide
go.drugbank.com/drugs/DB01128ApprovedInvestigationalBicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsProducts: BICALUTAMIDE KABI 50 MG FİLM TABLET, 20 ADET, CASODEX® 150 MGGefitinib
go.drugbank.com/drugs/DB00317ApprovedInvestigationalGefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. … Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Synonyms: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine, 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazolineCategories: MATE 1 Inhibitors, P-glycoprotein inhibitorsSomapacitan
go.drugbank.com/drugs/DB15093ApprovedInvestigationalSomapacitan, also known as NNC0195-0092,[A219136] is a growth hormone analog indicated to treat adults with growth hormone deficiency. … [A219146] Somapacitan was granted FDA approval on 28 August 2020.[L15666]
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Sogroya® 10 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet), Sogroya® 5 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet)Mefloquine
go.drugbank.com/drugs/DB00358ApprovedThe 2020 World Health Organization malaria report indicates a 60% decrease in the global malaria fatality rate between 2000 to 2019. … Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world.
Synonyms: [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol, 4-QUINOLINEMETHANOL, .ALPHA.-2-PIPERIDINYL-2,8-BIS(TRIFLUOROMETHYL)-, (R*,S*)-(±)-Mixtures: อาร์ทีซูเนทและเมฟลอควินไฮโดรคลอไรด์ 100/220 มก.Apremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigationalApremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. … [L7501] In July 2019, apremilast was granted a new FDA approval for the treatment of oral ulcers associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and
Synonyms: N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamideMixtures: OTEZLA 10 MG. 20 MG Y 30 MG, OTEZLA 10 MG. 20 MG Y 30 MGPetrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalA colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Mixtures: PCP 100 Kit, Dg Baby Vitamins A and DCategories: Compounds used in a research, industrial, or household settingNabumetone
go.drugbank.com/drugs/DB00461Approved[label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite acting as a potent COX inhibitor similar in structure to [naproxen]. … Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).
Synonyms: 4-(6-Methoxy-2-naphthalenyl)-2-butanone, 4-(6-Methoxy-2-naphthyl)-2-butanoneMixtures: NuDroxiPAK N-500Atracurium besylate
go.drugbank.com/drugs/DB00732ApprovedA non-depolarizing neuromuscular blocking agent with short duration of action.
Categories: Heterocyclic Compounds, 2-RingProducts: DEMATRAC 50 MG/5 ML İNFÜZYON İÇİN SOLÜSYON İÇEREN AMPUL, 10 AMPUL, ATRASYL 50 MG/5 ML I.V. ENJEKSIYON VE INFÜZYON IÇIN ÇÖZELTI IÇEREN AMPUL , 10 AMPULBedaquiline
go.drugbank.com/drugs/DB08903ApprovedInvestigationalBedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. … [L48506] Although the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key drugs [isoniazid] and [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB
Synonyms: 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-olCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates