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Recombinant stabilized RSV B prefusion F antigen
go.drugbank.com/drugs/DB18714ApprovedInvestigational[L48066] Abrysvo was first approved by the FDA in May 2023 for use in patients ≥60 years of age, and received subsequent approval in August 2023 for use in pregnant individuals for the protection of
CX-052075
go.drugbank.com/drugs/DB31655Approved[L53413,A274083] mNEXSPIKE was approved by the US FDA in June 2025 for use in patients who have been previously vaccinated with any COVID-19 vaccine and who are at a higher risk of severe outcomes from … CX-052075 is a nucleoside-modified messenger RNA (mRNA) encoding the N-terminal domain (NTD) and receptor-binding domain (RBD) of the spike glycoprotein of the SARS-CoV-2 Omicron variant sublineage LP.8.1
Amphetamine
go.drugbank.com/drugs/DB00182ApprovedIllicitInvestigational[A18540] The first product of Smith, Kline and French was approved by the FDA on 1976.[L5194] During World War II, amphetamine was used to promote wakefulness in the soldiers.
Venlafaxine
go.drugbank.com/drugs/DB00285ApprovedInvestigational[L43030] The immediate formulation of the drug, marketed as Effexor, was first approved by the FDA in 1993 and the extended-release formulation, Effexor XR, was later introduced in 1997.
Products: Nra-venlafaxine XRCysteamine
go.drugbank.com/drugs/DB00847ApprovedInvestigational[L15611] On August 25th 2020, the first ophthalmic solution for cystinosis requiring only 4 daily treatments was granted FDA approval.
Bismuth subsalicylate
go.drugbank.com/drugs/DB01294ApprovedVet approved[A230728, A230773] Bismuth subsalicylate was first approved by the FDA in 1939 and is now mainly used to relieve nausea, diarrhea, and gastrointestinal discomfort.
Clove oil
go.drugbank.com/drugs/DB11338ApprovedNutraceuticalThe FDA categorizes clove oil as generally recognized as safe (GRAS) for use in dental cement or as a food additive [F108].
Rimegepant
go.drugbank.com/drugs/DB12457ApprovedInvestigational[L11028] It received FDA approval on February 27, 2020 for the acute treatment migraine headache,[L11974] and was subsequently approved by the European Commission in April 2022 for both the treatment and … Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals.
Categories: Calcitonin Gene-Related Peptide Receptor AntagonistsVismodegib
go.drugbank.com/drugs/DB08828ApprovedInvestigational[A258608,L45803] In January 2012, vismodegib was approved by the FDA for the treatment of adult basal cell carcinoma.
Categories: Smoothened Receptor AntagonistsMirabegron
go.drugbank.com/drugs/DB08893ApprovedInvestigational[L32853] Mirabegron first received FDA approval in 2012, under the brand name Myrbetriq, for the treatment of adults with overactive bladder. … Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence.
Categories: Adrenergic beta-3 Receptor Agonists