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Lactulose
go.drugbank.com/drugs/DB00581ApprovedInvestigationaland its first clinical use for treating PSE was not until 1966. … Organization's List of Essential Medicines as one of the most effective and safe medicines employed in a health system[L6205], data regarding its optimal place in therapy is often ambiguous.
Categories: Drugs for ConstipationSynonyms: 4-O-beta-D-Galactopyranosyl-D-fructose, 4-O-beta-D-Galactopyranosyl-D-fructofuranoseAtoltivimab
go.drugbank.com/drugs/DB15898ApprovedInvestigational[A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions of antibodies were important for therapeutic benefit in animal models of EBOV infection. … [A222078] The chief surface target of EBOV particles is the GP<sub>1,2</sub> glycoprotein, which also appears on the surface of EBOV-infected cells, offering opportunities for both neutralizing and cytotoxic
Categories: Treatments for Ebola Virus DiseaseInsulin icodec
go.drugbank.com/drugs/DB16693ApprovedInvestigationalMay 2024 for the same indication. … [L51078]The US FDA subsequently approved insulin icodec in March 2026 for use as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. [L56102]
Categories: Drugs Used in DiabetesDyspnea
go.drugbank.com/conditions/DBCOND0024477Drugs: ReproterolSynonyms: Difficulty in breathing, DIB - Difficulty in breathingMinnelide
go.drugbank.com/drugs/DB17309InvestigationalSynonyms: 14-o-phosphonooxymethyltriptolide disodium salt, Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium salt (1:2), (3bs,4as,5ar,6r,6as,7as,7bs,Tazobactam
go.drugbank.com/drugs/DB01606ApprovedInvestigationalIt is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections. … Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved by the FDA in 2014[FDA label], providing wider antibacterial coverage for gram-negative infections
Mixtures: Zosyn in Galaxy Containers, Zosyn in Galaxy ContainersCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseLevoketoconazole
go.drugbank.com/drugs/DB05667ApprovedIt possesses most of the inhibitory effect towards steroidogenic enzymes, making it an attractive candidate for CS treatment with a potentially lower toxicity profile than its racemate. … changes in body composition, neuropsychiatric effects, changes in blood pressure and chemistry, and opportunistic infections.
Categories: Corticosteroids for Systemic UseDoravirine
go.drugbank.com/drugs/DB12301ApprovedInvestigational[L4562] Doravirine is formally indicated for the treatment of HIV-1 infection in adult patients with no prior antiretroviral treatment experience, further expanding the possibility and choice of therapeutic … Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.
Categories: Antivirals used in combination for the treatment of HIV infections, Antivirals for Systemic UseEtuvetidigene Autotemcel
go.drugbank.com/drugs/DB17593ApprovedInvestigational[L54693] WAS is a rare X-linked disorder caused by a mutation in the gene encoding the WAS protein, leading to a compromised immune system. … [A274878] The WAS protein is expressed on non-erythroid hematopoietic cells and regulates the function of actin filaments in the cytoskeleton.[A274878]
Tradipitant
go.drugbank.com/drugs/DB12580ApprovedInvestigational[A275353] Approved by the FDA on December 30, 2025, tradipitant is indicated for the prevention of vomiting induced by motion. … Tradipitant is a selective, high-affinity antagonist at human substance P/neurokinin-1 (NK-1) receptors.