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Displaying results 1661 - 1670 of 10000 in total
  1. Drug

    Fitusiran

    go.drugbank.com/drugs/DB15002
    ApprovedInvestigational

    Fitusiran is an antithrombin-directed double-stranded small interfering ribonucleic acid (siRNA) that is covalently linked to a ligand containing a triantennary N-acetylgalactosamine (GalNAc) moiety. … [L52860] Fitusiran was first approved by the FDA on March 28, 2025, as routine prophylaxis therapy to prevent or reduce the frequency of bleeding episodes associated with hemophilia A or B.

    Synonyms: SMALL INTERFERING RNA (SIRNA) INHIBITING ANTITHROMBIN LIVER PRODUCTION: DUPLEX OF ((2S,4R)-1-(1-((2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-16,16-BIS((3-((3-(5-((2-ACETAMIDO-2-DEOXY-.BETA., -D-GALACTOPYRANOSYL)OXY)PENTANAMIDO)PROPYL)AMINO)-3-OXOPR
  2. Drug

    Polydatin

    go.drugbank.com/drugs/DB11263
    Approved

    It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis [A27229]. … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure.

    Synonyms: Polydatin (E)-isomer, 3,4',5-trihydroxystilbene-3-β-d-glucoside
  3. Drug

    N(6)-(pyridoxal phosphate)-L-lysine

    go.drugbank.com/drugs/DB04083
    Experimental

    Synonyms: N(6)-(pyridoxal phosphate)-L-lysine, N6-((3-Hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methylene)-L-lysine
  4. Drug

    TIK-301

    go.drugbank.com/drugs/DB16909
    Experimental

    Synonyms: (R)-N-[2-(6-Chloro-5-Methoxy-1H-Indol-3-Yl)Propyl]Acetamide, N-((2r)-2-(6-chloro-5-methoxy-1h-indol-3-yl)propyl)acetamideCategories: Heterocyclic Compounds, 2-Ring
  5. Drug

    SD-0006

    go.drugbank.com/drugs/DB07943
    Experimental

    Synonyms: 5-p-chlorophenyl-3-[N-(2-hydroxyacetyl)piperidin-4-yl]-4-pyrimidin-4-yl-1H-pyrazole, 2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanolCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    R-348

    go.drugbank.com/drugs/DB06321
    Investigational

    Synonyms: 5-Fluoro-N-(4-methyl-3-propionylaminosulfonylphenyl)-N'-(4-(prop-2-ynyloxy)phenyl)-2,4-pyrimidinediamine
  7. Drug

    Nelonicline

    go.drugbank.com/drugs/DB19040
    Investigational

    Nelonicline is under investigation in clinical trial NCT01678755 (A Phase 2 Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia).

    Synonyms: 2-((3r,4s,5s,7s)-1-azaadamantan-4-yloxy)-5-phenyl-1,3,4-thiadiazole, rel-Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    SR-9011

    go.drugbank.com/drugs/DB14014
    Experimental

    SR-9011 is a REV-ERB agonist. … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues

    Synonyms: 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea

    go.drugbank.com/drugs/DB02277
    Experimental

    Synonyms: 1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea
  10. Drug

    Tapencarium

    go.drugbank.com/drugs/DB17821
    Investigational

    Synonyms: 5-[3,6-dibromo-9H-carbazol-9-yl]-N,N,N-trimethylpentan-1-aminium chlorideCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-Ring