TIK-301

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
TIK-301
DrugBank Accession Number
DB16909
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 280.75
Monoisotopic: 280.0978555
Chemical Formula
C14H17ClN2O2
Synonyms
  • (R)-N-[2-(6-Chloro-5-Methoxy-1H-Indol-3-Yl)Propyl]Acetamide
  • Beta-methyl-6-chloromelatonin
  • LY-156,735
  • LY-156735
  • N-((2r)-2-(6-chloro-5-methoxy-1h-indol-3-yl)propyl)acetamide
External IDs
  • LY 156735
  • LY-156,735
  • LY-156735
  • LY156735
  • PD-6735
  • TIK 301
  • TIK-301
  • TIK301

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
3ZX95B1ZWK
CAS number
118702-11-7
InChI Key
RKHCTAKUYDTFHE-QMMMGPOBSA-N
InChI
InChI=1S/C14H17ClN2O2/c1-8(6-16-9(2)18)11-7-17-13-5-12(15)14(19-3)4-10(11)13/h4-5,7-8,17H,6H2,1-3H3,(H,16,18)/t8-/m0/s1
IUPAC Name
N-[(2R)-2-(6-chloro-5-methoxy-1H-indol-3-yl)propyl]acetamide
SMILES
COC1=CC2=C(NC=C2[C@@H](C)CNC(C)=O)C=C1Cl

References

General References
Not Available
ChemSpider
189853
ChEMBL
CHEMBL4079759
ZINC
ZINC000000021620
Wikipedia
TIK-301

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0223 mg/mLALOGPS
logP3.09ALOGPS
logP2.12Chemaxon
logS-4.1ALOGPS
pKa (Strongest Acidic)15.35Chemaxon
pKa (Strongest Basic)-1.4Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area54.12 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity75.56 m3·mol-1Chemaxon
Polarizability29.5 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at September 02, 2022 16:37 / Updated at September 12, 2023 18:32