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Displaying results 1671 - 1680 of 10000 in total
  1. Drug

    Choline

    go.drugbank.com/drugs/DB00122
    ApprovedInvestigationalNutraceutical

    It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. … A basic constituent of lecithin that is found in many plants and animal organs.

    Mixtures: Prev-Rx, Super Daily No 2Synonyms: N,N,N-trimethylethanol-ammonium, N-trimethylethanolamine
  2. Drug

    CX-052075

    go.drugbank.com/drugs/DB31655
    Approved

    [L53413,A274083] mNEXSPIKE was approved by the US FDA in June 2025 for use in patients who have been previously vaccinated with any COVID-19 vaccine and who are at a higher risk of severe outcomes from … CX-052075 is a nucleoside-modified messenger RNA (mRNA) encoding the N-terminal domain (NTD) and receptor-binding domain (RBD) of the spike glycoprotein of the SARS-CoV-2 Omicron variant sublineage LP.8.1

  3. Target

    Protein c-Fos

    go.drugbank.com/bio_entities/BE0001126
    TargetHumans

    In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. … Has a critical function in regulating the development of cells destined to form and maintain the skeleton.

    Polypeptides: Protein c-FosSynonyms: Cellular oncogene fos, Proto-oncogene c-Fos
  4. Drug

    Coagulation factor X human

    go.drugbank.com/drugs/DB13148
    ApprovedInvestigational

    Coagulation Factor X is a vitamin K-dependent, liver-produced serine protease that serves as the first enzyme in the coagulation cascade to form fibrin. … Inherited factor X deficiency is a rare autosomal recessive bleeding disorder that is estimated to occur in 1:1 000 000 individuals up to 1:500 carriers [A31471].

    Synonyms: Factor X, Coagulation factor XMixtures: BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTION, OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU
  5. Indication

    T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

    go.drugbank.com/conditions/DBCOND0082251
    Drugs: Polatuzumab vedotin
    Synonyms: Malignant lymphoma, large B-cell, diffuse, no International Classification of Diseases for Oncology subtype, Malignant lymphoma, large B-cell, diffuse, no ICD-O subtype
  6. Drug

    Cantharidin

    go.drugbank.com/drugs/DB12328
    ApprovedInvestigational

    [A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin to a female beetle as a copulatory gift during mating. … [A32892] Nevertheless, it gained its first FDA approval on Jul 21, 2023, under the brand name YCANTH™ by Verrica Pharmaceuticals for the treatment of molluscum contagiosum in adult and pediatric patients

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Lithium cation

    go.drugbank.com/drugs/DB01356
    ApprovedInvestigationalWithdrawn

    Lithium can also be used to augment other antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. … The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several

    Synonyms: Lithium ion, Lithium, ionCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  8. Drug

    Fidanacogene elaparvovec

    go.drugbank.com/drugs/DB16783
    ApprovedInvestigational

    [L46691] Hemophilia B is a rare X-linked genetic disorder characterized by abnormal coagulation due to dysfunctional coagulation factor IX with a male incidence estimated to be 1 in 30,000 male births … Factor IX (FIX) deficiency) who are negative for neutralizing antibodies to variant AAV serotype Rh74.

  9. Drug

    Olmesartan

    go.drugbank.com/drugs/DB00275
    ApprovedInvestigational

    Olmesartan is commonly used for the management of hypertension and Type 2 Diabetes-associated nephropathy, particularly in patients who are unable to tolerate ACE inhibitors. … ARBs such as olmesartan have been shown in a number of large-scale clinical outcomes trials to improve cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression

    Mixtures: OPENVAS CO, ALMETEC-COCategories: Antihypertensive Agents Indicated for Hypertension, Agents Acting on the Renin-Angiotensin System
  10. Drug

    Bulevirtide

    go.drugbank.com/drugs/DB15248
    ApprovedInvestigational

    It was first approved for use in the EU on May 28, 2020; bulevirtide has been granted PRIME scheme eligibility and Orphan Drug Designation by the European Medicines Agency. … [A226305] Bulevirtide, also known as Hepcludex, is a first-in-class entry inhibitor for the treatment of chronic Hepatitis D infection developed by MYR Pharmaceuticals, now part of Gilead.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use