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Displaying results 1681 - 1690 of 10000 in total
  1. Drug

    Fitusiran

    go.drugbank.com/drugs/DB15002
    ApprovedInvestigational

    [L52865] By causing the degradation of antithrombin mRNA and promoting thrombin generation, fitusiran works to restore hemostasis in patients with hemophilia.[A273770] … Fitusiran is an antithrombin-directed double-stranded small interfering ribonucleic acid (siRNA) that is covalently linked to a ligand containing a triantennary N-acetylgalactosamine (GalNAc) moiety.

    Synonyms: SMALL INTERFERING RNA (SIRNA) INHIBITING ANTITHROMBIN LIVER PRODUCTION: DUPLEX OF ((2S,4R)-1-(1-((2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-16,16-BIS((3-((3-(5-((2-ACETAMIDO-2-DEOXY-.BETA., -D-GALACTOPYRANOSYL)OXY)PENTANAMIDO)PROPYL)AMINO)-3-OXOPRCategories: Nucleic Acids, Nucleotides, and Nucleosides
  2. Drug

    Indralin

    go.drugbank.com/drugs/DB18220
    Experimental

    Synonyms: 2-thiophenecarboxylic acid, 5-((1e)-2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propen-1-yl)-, 5-((1e)-2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propen-1-yl)-2-thiophenecarboxylic acidCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Aminoflavone

    go.drugbank.com/drugs/DB19077
    Investigational

    Aminoflavone is under investigation in clinical trial NCT01015521 (Efficacy Study of Aminoflavone Prodrug to Treat Breast Cancer).

    Synonyms: 4h-1-benzopyran-4-one, 5-amino-2-(4-amino-3-fluorophenyl)-6,8-difluoro-7-methyl-, 5-amino-2-(4-amino-3-fluorophenyl)-6,8-difluoro-7-methyl-4h-1-benzopyran-4-oneCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates
  4. Drug

    Sutezolid

    go.drugbank.com/drugs/DB11905
    Investigational

    Sutezolid has been used in trials studying the treatment of Tuberculosis.

    Synonyms: N-{[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide, ACETAMIDE, N-((3-(3-FLUORO-4-(4-THIOMORPHOLINYL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL)-, (S)-Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    3-[2,6,8-Trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate

    go.drugbank.com/drugs/DB03973
    Experimental

    Synonyms: 5-Deoxy-5-{2,6,8-trioxo-7-[3-(phosphonooxy)propyl]-1,2,3,6,7,8-hexahydro-9H-purin-9-yl}-D-arabinitol, 3-[2,6,8-Trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate
  6. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    into active metabolites: (+)-tramadol and its primary metabolite (+)-O-desmethyl-tramadol (M1) are agonists of the μ opioid receptor while (+)-tramadol inhibits serotonin reuptake and (-)-tramadol inhibits … It is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th of the potency of [morphine].

    Mixtures: ZALDIAR 37,5 MG/325 MG FİLM KAPLI TABLET, 10 ADET, ZALDIAR 37,5 MG/325 MG FİLM KAPLI TABLET, 20 ADETCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor Antagonists
  7. Drug

    Avoralstat

    go.drugbank.com/drugs/DB12120
    Investigational

    Avoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema.

    Synonyms: 3-(2-((4-Carbamimidoylphenyl)carbamoyl)-4-ethenyl-5-methoxyphenyl)-6-((cyclopropylmethyl)carbamoyl)pyridine-2-carboxylic acid, 3-[2-(4-carbamimidoyl-phenylcarbamoyl)-5-methoxy-4-vinyl-phenyl]-6-(cyclopropylmethyl-carbamoyl)-pyridine-2-carboxylic acidCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Fexuprazan

    go.drugbank.com/drugs/DB16078
    Investigational

    Abeprazan is under investigation in clinical trial NCT04341454 (Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Acute or Chronic Gastritis).

    Synonyms: 1H-PYRROLE-3-METHANAMINE, 5-(2,4-DIFLUOROPHENYL)-1-((3-FLUOROPHENYL)SULFONYL)-4-METHOXY-N-METHYL-, 5-(2,4-DIFLUOROPHENYL)-1-((3-FLUOROPHENYL)SULFONYL)-4-METHOXY-N-METHYL-1H-PYRROLE-3-METHANAMINECategories: Heterocyclic Compounds, 1-Ring, Alimentary Tract and Metabolism
  9. Drug

    APTO-253

    go.drugbank.com/drugs/DB17143
    Investigational

    Synonyms: 1h-imidazo(4,5-f)(1,10)phenanthroline, 2-(5-fluoro-2-methyl-1h-indol-3-yl)-, 2-(5-fluoro-2-methyl-1h-indol-3-yl)-1h-imidazo(4,5-f)(1,10)phenanthrolineCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-Ring
  10. Drug

    1,​2-​Dioleoyl-​sn-​glycero-​3-​phospho-​L-​serine

    go.drugbank.com/drugs/DB18573
    Experimental

    Synonyms: 4,6,10-trioxa-5-phosphaoctacos-19-enoic acid, 2-amino-5-hydroxy-11-oxo-8-(((9z)-1-oxo-9-octadecen-1-yl)oxy)-, 5-oxide, (2s,8r,19z)-, L-serine, 2,3-bis((1-oxo-9-octadecenyl)oxy)propyl hydrogen phosphate (ester), (r-(z,z))-