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Displaying results 161 - 170 of 149866 in total
  1. Drug

    Linvoseltamab

    go.drugbank.com/drugs/DB17447
    ApprovedInvestigational

    Linvoseltamab (INN), marketed as Lynozyfic™, is a bispecific human IgG4 monoclonal antibody developed by Regeneron that promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma … This mechanism results in the targeted release of cytokines such as IL-2, IL-6, and IFN-gamma, promoting the selective lysis of BCMA-expressing cells and offering a novel immunotherapeutic approach for

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMA
  2. Drug

    Tapinarof

    go.drugbank.com/drugs/DB06083
    ApprovedInvestigational

    Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. … It is available as a topical cream to be applied to the affected area once daily.

    Synonyms: 3,5-Dihydroxy-4-isopropyl-trans-stilbene
  3. Drug

    Follitropin

    go.drugbank.com/drugs/DB00066
    ApprovedInvestigational

    Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta … The nomenclature “beta” differentiates it from another recombinant human FSH product that was marketed earlier as follitropin alpha.

    Mixtures: MENOGON 75 IU Powder and Solvent for solution for Injection, Pergoveris Powder and Solvent for Solution for Injection 150iu/75iuCategories: Amino Acids, Peptides, and Proteins, Gonadotropins and Antigonadotropins
  4. Drug

    Turofexorate isopropyl

    go.drugbank.com/drugs/DB12719
    Investigational

    Fxr 450 is under investigation in clinical trial NCT00509756 (Study Evaluating Turofexorate isopropyl in Healthy Japanese Men).

    Synonyms: Turofexorate isopropyl
  5. Drug

    Vayarin

    go.drugbank.com/drugs/DB09328
    Approved

    Vayarin is an orally administered prescription medical food for the clinical dietary management of complex lipid imbalances thought to be associated with ADHD. … Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional requirements of children with ADHD, the dietary management of which cannot be achieved with

    Synonyms: Phosphatidylserine, DHA, and EPA
  6. Drug

    Pariglasgene brecaparvovec

    go.drugbank.com/drugs/DB16801
    Approved

    [L64050,L64051] It delivers a functional copy of the human G6PC gene, under the control of native G6PC promoter and enhancer elements, to hepatocytes, resulting in the production of normally functioning … [L64050,L64051] The approval covers adults and pediatric patients 8 years of age and older and was based on a statistically significant reduction in daily cornstarch intake, a surrogate endpoint, with

    Categories: Cellular and Gene TherapySynonyms: Recombinant adeno-associated virus serotype 8 vector encoding human glucose-6-phosphatase-alpha, Recombinant adeno-associated virus serotype 8 vector encoding human glucose-6-phosphatase-alpha (G6Pase or G6PC)
  7. Drug

    Atacicept

    go.drugbank.com/drugs/DB06399
    ApprovedInvestigational

    Atacicept is a recombinant fusion glycoprotein that joins the ligand-binding portion of the human TACI receptor to a modified IgG1 Fc domain, allowing it to bind and neutralize two cytokines: B cell activating … factor (BAFF) and A Proliferation Inducing Ligand (APRIL).

    Categories: Amino Acids, Peptides, and Proteins, Recombinant ProteinsSynonyms: Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein (Fc5), TACI-IG
  8. Drug

    Alpha-1-proteinase inhibitor

    go.drugbank.com/drugs/DB00058
    ApprovedInvestigational

    Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.

    Categories: Human alpha-1 Proteinase Inhibitor, Enzymes and CoenzymesSynonyms: Recombinant secretory leucocyte protease inhibitor, Recombinant secretory leukocyte protease inhibitor
  9. Drug

    Recombinant human palmitoyl-protein thioesterase-1

    go.drugbank.com/drugs/DB17949
    Experimental

    Synonyms: Recombinant human palmitoyl-protein thioeserase-1, Recombinant human palmitoyl-protein thioesterase-1
  10. Drug

    Human Recombinant Bone Morphogenetic Protein 4

    go.drugbank.com/drugs/DB17372
    Investigational

    Synonyms: Human Recombinant Bone Morphogenetic Protein 4, RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 4