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Displaying results 161 - 170 of 161257 in total
  1. Drug

    Rizatriptan

    go.drugbank.com/drugs/DB00953
    ApprovedInvestigational

    Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist.

    Categories: Serotonin 5-HT1 Receptor Agonists, Selective Serotonin 5-HT1 Receptor AgonistsSynonyms: N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine
  2. Drug

    Gimeracil

    go.drugbank.com/drugs/DB09257
    ApprovedInvestigational

    This allows higher concentrations of 5-FU to be achieved with a lower dose of tegafur, thereby also reducing toxic side effects. … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug that acts on rapidly dividing cancer cells.

    Mixtures: TS-ONE CAPSULE 25, TS-ONE CAPSULE 25Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Foxy-5

    go.drugbank.com/drugs/DB13034
    Investigational

    Foxy-5 has been used in trials studying the treatment of Prostate Cancer, Colorectal Cancer, Metastatic Colon Cancer, Metastatic Breast Cancer, and Metastatic Prostate Cancer.

    Synonyms: Foxy-5
  4. Drug

    Chlorothymol

    go.drugbank.com/drugs/DB19375
    Approved

    Chlorotymol is a [Thymol] derivative.

    Synonyms: 4-chlor-2-isopropyl-5-methylphenol, 4-chloro-5-methyl-2-(1-methylethyl)phenol
  5. Drug

    5-Bromonicotinamide

    go.drugbank.com/drugs/DB01854
    Experimental

    Synonyms: 5-Bromonicotinamide
  6. Drug

    5'-Guanylylmethylenebisphosphonate

    go.drugbank.com/drugs/DB03725
    Experimental

    Synonyms: 5'-Guanosyl-methylene-triphosphate, 5'-GuanylylmethylenebisphosphonateCategories: Heterocyclic Compounds, 2-Ring
  7. Drug

    5-Bromothienyldeoxyuridine

    go.drugbank.com/drugs/DB03804
    Experimental

    Synonyms: 5-Bromothienyldeoxyuridine
  8. Drug

    5-Oxoprolinal

    go.drugbank.com/drugs/DB03901
    Experimental

    Synonyms: 5-Oxoprolinal, 5-KetoprolinalCategories: Pyroglutamyl-Peptidase I, antagonists & inhibitors
  9. Drug

    Ceritinib

    go.drugbank.com/drugs/DB09063
    ApprovedInvestigational

    About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ALK (anaplastic lymphoma kinase), which … The FDA approved ceritinib in April 2014 due to a surprisingly high response rate (56%) towards crizotinib-resistant tumours and has designated it with orphan drug status.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane-2-sulfonamide
  10. Drug

    Cromoglicic acid

    go.drugbank.com/drugs/DB01003
    ApprovedInvestigational

    A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.

    Synonyms: 5-[3-(2-carboxy-4-oxo-4H-5-chromenyloxy)-2-hydroxypropoxy]-4-oxo-4H-2-chromenecarboxylic acidMixtures: OSMOCROM-N ®