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Leucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigational[L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic
Products: Bulk Vial) 10mg/ml, Lederle Leucovorin 50mg/vialBlinatumomab
go.drugbank.com/drugs/DB09052ApprovedInvestigationalBlinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through … [A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of malignant B-cells.
Products: BLINCYTO® 38.5 MCG/VIAL, BLINCYTO POWDER FOR INFUSION 35 MCG/VIALNystatin
go.drugbank.com/drugs/DB00646ApprovedInvestigationalVet approvedNystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably Candida species. It is one of the most effective antifungal agents synthesized by bacter...
Mixtures: ORIDERMYL EAR OINTMENT, NISTATINA + OXIDO DE ZINCProducts: Nilstat Vag Tab 100000unit, Nilstat Vag Crm 100000unit/gmAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceutical[A234044] It plays an essential function in calcium homeostasis and bone metabolism. … Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D].
Categories: Vitamin D and AnaloguesSynonyms: 1α-hydroxyvitamin D3, 1α-hydroxy-vitamin D3Ceftriaxone
go.drugbank.com/drugs/DB01212ApprovedInvestigationalCeftriaxone is a commonly used antimicrobial due to its good activity against multi-drug resistant Enterobacteriaceae, its relatively safe adverse effect profile, and its long half-life which allows for … [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges[A215582], eyes[A215647], and inner ear[A215627].
Mixtures: ROCEPHIN VIAL 1G IM, ROCEPHIN VIAL 500MG IMCategories: P-glycoprotein inhibitorsNorgestrel
go.drugbank.com/drugs/DB09389ApprovedNorgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception.
Mixtures: Norgestrel/Ethinyl EstradiolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesZolmitriptan
go.drugbank.com/drugs/DB00315ApprovedInvestigational[A193791] Triptans can be administered alone or in combination with an NSAID like [naproxen], and represent the current "gold standard" for acute migraine treatment.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: Van-zolmitriptan, Van-zolmitriptan ODTBudesonide
go.drugbank.com/drugs/DB01222ApprovedInvestigationalBudesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. Budesonide was granted FDA approval o...
Mixtures: SYMBICORT PI 80/4.5UG120ED, SYMBICORT PI 80/4.5UG120EDCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesAzacitidine
go.drugbank.com/drugs/DB00928ApprovedInvestigationalAs an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and inhibiting protein and DNA synthesis. … [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA, azacytidine has been used mainly used in the treatment of myelodysplastic syndromes (MDS) and acute
Synonyms: 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-oneProducts: AZACT SPAL-P 100 (Azacitidine powder for suspension for injection, 100 mg/vial), XPREZA 100 INJECTION 100 MG/VIALOctasulfur
go.drugbank.com/drugs/DB09353ApprovedSulfur seems to have an antibacterial activity. It has been also used for acne.
Mixtures: Dr Lift Blemish, AvarProducts: Pharmassist Clarifex Ph Mud Crm 3.0%, 111MedCo 6% Sulfur Skin Cleansing Bar