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Displaying results 161 - 170 of 10000 in total
  1. Drug

    Sipavibart

    go.drugbank.com/drugs/DB21908
    ApprovedInvestigational

    [A274098] It works by binding to the SARS-CoV-2 spike protein receptor binding domain (RBD), neutralize the virus and preventing its entry into the host cell. … [A274088] Sipavibart is approved for the pre-exposure prophylaxis treatment of COVID-19 in immunocompromised patients.[L53418]

    Synonyms: Gamma1 heavy chain Homo sapiens (1-455) [VH (Homo sapiens IGHV3-9*01 (94.9%) -(IGHD) -IGHJ1*01 (90.9%) L123>T (120), CDR-IMGT [8.8.18] (26-33.51-58.97-114)) (1-125) -Homo sapiens IGHG1*03, G1m3, nG1m1, Immunoglobulin G1-lambda, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody
  2. Drug

    Icanbelimod

    go.drugbank.com/drugs/DB21572
    Experimental

    The usage of the INN stem '-imod' in the name indicates that Icanbelimod is a immunomodulator, both stimulant/suppressive and stimulant. Icanbelimod has a monoisotopic molecular weight of 409.18 Da.

    Synonyms: S1p receptor agonist 1
  3. Drug

    Tividenofusp alfa

    go.drugbank.com/drugs/DB17628
    ApprovedInvestigational

    Tividenofusp alfa is a recombinant human IDS fused to a monoclonal antibody that targets the human insulin receptor (HIR), utilizing receptor-mediated transcytosis to gain access to the central nervous … While standard ERTs can treat systemic symptoms, they are unable to cross the blood-brain barrier (BBB) to address the progressive cognitive decline and neurological impairment seen in the majority of

    Synonyms: ENZYME TRANSPORT VEHICLE SPECIFIC FOR THE TRANSFERRIN RECEPTOR FUSED TO IDURONATE 2-SULFATASE, - L-iduronate sulfate sulfatase, EC:3.1.6.13) pro-protein (1-525), fused via the peptide linker 526 GGGGS 530 to a human immunoglobulin G1 C-terminal Fc fragment (531-757) variant (L 544>A, L 545>A, T
  4. Drug

    KRN-633

    go.drugbank.com/drugs/DB33594
    Experimental

    Synonyms: Vegf receptor tyrosine kinase inhibitor iii
  5. Drug

    Levonorgestrel

    go.drugbank.com/drugs/DB00367
    ApprovedInvestigational

    [L7823] In addition to the above uses, levonorgestrel is used as a component of long-term combination contraceptives. … to older emergency contraceptive regimens.

    Mixtures: Vienva TM, Vienva TMCategories: Sex Hormones and Modulators of the Genital System
  6. Drug

    Nadroparin

    go.drugbank.com/drugs/DB08813
    ApprovedInvestigationalWithdrawn

    Nadroparin halts the coagulation pathway by inhibiting the activation of thrombin (factor IIa) by factor Xa. … Nadroparin is a low molecular weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor II and factor Xa.

    Products: FRAXIPARINE TX 1 ML
  7. Drug

    Tobramycin

    go.drugbank.com/drugs/DB00684
    ApprovedInvestigational

    the eye (ophthalmic). … [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a variety of infections caused by susceptible bacteria.

    Mixtures: TQ TOBRAOFTAL D® SUSPENSION OFTALMICA ESTERIL, TQ TOBRAOFTAL D® SUSPENSION OFTALMICA ESTERILProducts: TQ TOBRAOFTAL®. SOLUCION OFTALMICA ESTERIL
  8. Drug

    Hypromellose

    go.drugbank.com/drugs/DB11075
    ApprovedInvestigational

    It is a commonly used as a delivery component in oral pharmaceutical products that provides the release of a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong … It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations [A24840].

    Mixtures: GenTeal Moderate to SevereProducts: GenTeal Mild to Moderate
  9. Drug

    Levocetirizine

    go.drugbank.com/drugs/DB06282
    ApprovedInvestigational

    [L7694] Levocetirizine has greater affinity for the histamine H<sub>1</sub> receptor than cetirizine.[L7694] Levocetirizine was granted FDA approval in 1995.[L7694] … Levocetirizine is a selective histamine H<sub>1</sub> antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of [cetirizine].

    Mixtures: NORAVER ® GFAST CAPSULAS BLANDAS CONTRA LOS SINTOMAS DE LA GRIPAProducts: LEVOSETIL 5 MG FILM TABLET ,20 TB, LEVOSETIL 5 MG FILM TABLET ,40 TB
  10. Drug

    Levocarnitine

    go.drugbank.com/drugs/DB00583
    ApprovedInvestigational

    It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

    Products: CARNITENE 1 G TEK DOZ ORAL SOLÜSYON, 10 ML, T-KARNIT 1 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON, 10 ADET