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Fluoxetine
go.drugbank.com/drugs/DB00472ApprovedInvestigationalVet approved[A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor AntagonistsProducts: FLUOXETIN-NEURAX 20 MG TThiosulfuric acid
go.drugbank.com/drugs/DB09499ApprovedInvestigationalSodium thiosulfate is also used to reduce the risk of ototoxicity associated with [cisplatin]. … Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching
Products: TIOSULFATO DE SODIO 20%Abacavir
go.drugbank.com/drugs/DB01048ApprovedInvestigationalChemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. … In vivo, abacavir sulfate dissociates to its free base, abacavir.
Mixtures: ABACAVIR E LAMIVUDINA LUPIN, ABACAVIR E LAMIVUDINA LUPINCategories: Antivirals used in combination for the treatment of HIV infectionsCocaine
go.drugbank.com/drugs/DB00907ApprovedIllicitInvestigationalIt also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. … An alkaloid ester extracted from the leaves of plants including coca.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigational[L26966,L26976] In November 2021, Health Canada [L39115] and the EMA [L39272] approved the vaccine to be administered as a booster dose approximately six months after the second dose. … [L36025] Currently, sufficient data are not available to determine the longevity of protection against COVID-19, nor direct evidence that the vaccine prevents the transmission of the SARS-CoV-2 virus
Estradiol
go.drugbank.com/drugs/DB00783ApprovedInvestigationalVet approved[DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination oral contraceptive pills (OCPs). … Ethinyl estradiol is different from estradiol due to its higher biovailability and increased resistance to metabolism, rendering it more suitable for oral administration.
Categories: Sex Hormones and Modulators of the Genital SystemProducts: JUVENUM E, ESTRADERM TTS DE 100 MCGApazunersen
go.drugbank.com/drugs/DB16981InvestigationalApazunersen is an antisense oligonucleotide designed to target and inhibit the expression of UBE3A-AS. It is being investigated for the treatment of Angelman Syndrome.[L46772]
Categories: Antisense Oligonucleotide Specific to the Antisense Transcript of UBE3AFinasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigationalCompared to alpha-blockers that focus on providing the rapid relief of symptoms, 5α-reductase inhibitors aim to target the underlying disease by blocking the effects of the primary androgen involved in … [L6244,L10565] In 1998, it was approved by the FDA to treat male pattern hair loss.
Filgrastim
go.drugbank.com/drugs/DB00099ApprovedInvestigationalFilgrastim mimics the biological actions of G-CSF to increase the levels of neutrophils in the blood. … [L40773] A long-acting, pegylated G-CSF, [pegfilgrastim], was made available to increase the duration of action of the drug.
Products: E/0.5ML, E/0.5MLNaltrexone
go.drugbank.com/drugs/DB00704ApprovedInvestigationalVet approvedThe FDA has approved naltrexone for the treatment of alcohol dependence. … Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome