Search
Didanosine
go.drugbank.com/drugs/DB00900ApprovedInvestigationalThis modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigational[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. … In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment
Categories: Antihypertensives for Pulmonary Arterial HypertensionProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedProgesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. … Please see [Medroxyprogesterone acetate], [Megestrol acetate], [Dydrogesterone] and [Hydroxyprogesterone] entries for information on various other forms of progesterone.
Categories: Hormonal Contraceptives for Systemic UseObeticholic acid
go.drugbank.com/drugs/DB05990ApprovedInvestigational[A192786] Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. … [L34650] Obeticholic acid is currently being considered for FDA approval to treat fibrosis caused by non-alcoholic liver steatohepatitis (NASH).
Categories: Farnesoid X Receptor Agonist, Farnesoid X Receptor AgonistsSecnidazole
go.drugbank.com/drugs/DB12834ApprovedInvestigational[A245503] Secnidazole has been available in many other countries in Europe, Asia, South America, and Africa for decades. … [A245503, A245508] In September 2017, FDA approved secnidazole under the market name Solosec for the treatment of trichomoniasis and bacterial vaginosis.[L39524]
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UsePeramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalfor no more than two days. … The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseEdotreotide gallium Ga-68
go.drugbank.com/drugs/DB15494Approved[L8603] Edotreotide gallium Ga-68 is indicated for localizing somatostatin receptor positive neuroendocrine tumors by positron emission tomography. … [L8597] [Dotatate gallium Ga-68] is used for a similar indication.[A185852] Dotatate gallium Ga-68 has lower tumor uptake but this data is highly variable between patients.
Human papillomavirus type 31 L1 capsid protein antigen
go.drugbank.com/drugs/DB10310ApprovedInvestigationalIt is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 31. … Human papillomavirus type 31 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection.
Mixtures: GARDASIL 9 SUSPENSION FOR INJECTIONTrioxsalen
go.drugbank.com/drugs/DB04571ApprovedWithdrawnIn research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage.[3] The compound is has been explored for development of antisense oligonucleotides that can be … It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and hand eczema.
Categories: Antipsoriatics for Systemic Use, Antipsoriatics for Topical UseBismuth subcitrate potassium
go.drugbank.com/drugs/DB09275ApprovedInvestigationalA bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)