Edotreotide gallium Ga-68

DB15494ApprovedSmall molecule

Edotreotide gallium Ga-68 is a radioactive diagnostic agent used in PET scans for somatostatin receptor positive neuroendocrine tumors in adult and pediatric patients. Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA).

Mechanism: Edotreotide gallium Ga-68 binds to somatostatin receptors, with higher affinity for somatostatin receptor type 2, where it emits beta particle radiation for detection by positron emission tomography (PET).
Curator reviewed · 1 reference
Primary indication: Edotreotide gallium Ga-68 is a radioactive diagnostic compound used in positron emission tomography (PET) for diagnose somatostatin receptor positive neuroendocrine tumors in pediatrics and adults.Curator reviewed · 1 structured indication
Formula / weight: C₆₅H₈₉GaN₁₄O₁₈S₂ · 1486.55 g/mol (avg)
First approval: United States, 2019 · European Union, 2020
Also known as: Gallium (68Ga) edotreotide · Gallium edotreotide Ga-68 · Gallium Ga 68-dotatoc · Gallium Ga 68-edotreotide · Gallium Ga-68 edotreotide
Brand names: Somakit TOC

Resolves to

Compound

UNIIY68179SY2LCAS2101630-92-4

Clinical / RWD

RxNorm2199391ATCV09IX09

Structure

InChIKeyPZBPHYLKIMOZPR-FIYGWYQWSA-KSMILES

[68Ga+3].C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)CN2CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC2)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@H](CC2=CNC3=C2C=CC=C3)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1

Targets

P30874SSTR2P35346SSTR5P32745SSTR3P30872SSTR1

What you can answer from here — as of September 08, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

5Drug interactionsStructured to mechanism, not free text

5Clinical trialsPhase, status and sponsor resolved per trial

1Structured indicationCondition, population, route and combination as fields, not prose

4Marketed productsAcross 4 countries and 4 labellers

1ATC codeIncluding every combination product, plus 4 drug categories

12+ReferencesStructured and connected to the statements they support

Which drugs share a target with Edotreotide gallium Ga-68, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account