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Displaying results 1701 - 1710 of 10000 in total
  1. Drug

    Linaclotide

    go.drugbank.com/drugs/DB08890
    ApprovedInvestigational

    Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C (G-CC) agonist. … [A260276] It is also a homolog of a heat-stable enterotoxin derived from _Escherichia coli_, the first natural ligand that activates GC-C.

  2. Drug

    Ledipasvir

    go.drugbank.com/drugs/DB09027
    Approved

    In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) recommend ledipasvir as a first line … Its use has also proven successful in the treatment of HCV in patients co-infected with HIV [A19627].

  3. Drug

    Molsidomine

    go.drugbank.com/drugs/DB09282
    ApprovedWithdrawn

    Interestingly, it is being studied as being a preventive measure in cerebral infarction [A31932]. … Molsidomine is an orally active, long-acting vasodilator, which belongs to the class of medications known as syndnones.

    Categories: Vasodilators Used in Cardiac Diseases
  4. Drug

    Influenza A virus A/Kansas/14/2017 X-327 (H3N2) antigen (UV, formaldehyde inactivated)

    go.drugbank.com/drugs/DB15520
    ApprovedWithdrawn

    Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.

    Mixtures: INFLUVAC TETRA, SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE 0.5 ML
  5. Drug

    Undecylenic acid

    go.drugbank.com/drugs/DB11117
    Approved

    It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones [L1891]. … Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat.

    Mixtures: Desenex Medicated Spray-ON Powder, Desenex Medicated Spray-ON PowderProducts: Pinceladas Goyescas Original Brush on Fungicide
  6. Drug

    Darunavir

    go.drugbank.com/drugs/DB01264
    ApprovedInvestigational

    [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066]

    Mixtures: VIRONTAR N COMPRIMIDOS RECUBIERTOS, VIRONTAR N COMPRIMIDOS RECUBIERTOSCategories: Antivirals used in combination for the treatment of HIV infections
  7. Drug

    Influenza B virus B/Phuket/3073/2013 recombinant hemagglutinin antigen

    go.drugbank.com/drugs/DB10779
    ApprovedInvestigational

    Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.

    Mixtures: Fluarix Tetra Injektionssuspension in einer Fertigspritze
  8. Drug

    Nitrous acid

    go.drugbank.com/drugs/DB09112
    ApprovedInvestigational

    It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. … There is also research to investigate its applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and Pseudomonas aeruginosa infections.

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Anakinra

    go.drugbank.com/drugs/DB00026
    ApprovedInvestigational

    [L35415] Since IL-1 has an important role in inflammation and immunological responses, anakinra is also used for the off-label treatment of inflammatory diseases. … [A247265] On November 8, 2022, the FDA issued an emergency use authorization (EUA) of anakinra for the treatment of COVID-19 in hospitalized patients who are at risk of progressing to severe respiratory

    Synonyms: IL-1RA
  10. Drug

    Rosiglitazone

    go.drugbank.com/drugs/DB00412
    ApprovedInvestigational

    Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. … It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl).

    Categories: Drugs Used in DiabetesInternational brands: Sheng Min