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Telaprevir
go.drugbank.com/drugs/DB05521ApprovedWithdrawnHCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. … Approved in May 2011 by the FDA, Incivek was indicated for the treatment of HCV genotype 1 in combination with [DB00811], [DB00008], and [DB00022] [FDA Label].
Synonyms: (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydrocyclopenta(c)pyrrole-1-carboxamideIsoflavone
go.drugbank.com/drugs/DB12007ApprovedInvestigationalWithdrawnIsoflavone is found as one of constituents in oral over-the-counter dietary supplements indicated for improved bone mass density and body fat regulation. … Soybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram [A33103].
Lutetium Lu-177 vipivotide tetraxetan
go.drugbank.com/drugs/DB16778ApprovedInvestigationalIt consists of a radionuclide, [lutetium Lu-177], linked to a moiety that binds to PSMA, a transmembrane protein that is expressed in prostate cancer. … [L43787] In December 2022, lutetium Lu-177 vipivotide tetraxetan was approved by the EMA.[L43787,L45533]
Categories: Compounds used in a research, industrial, or household settingPotassium cation
go.drugbank.com/drugs/DB01345ApprovedThe balance between potassium and sodium is maintained by ion pumps in the cell membrane. … The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential.
Synonyms: Potassium ion, Potassium (ion)Mixtures: POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 1000 CC SETLI, POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 1000 CC SETSİZGenistein
go.drugbank.com/drugs/DB01645InvestigationalExperimentally, it has been shown to induce G2 phase arrest in human and murine cell lines. Additionally, genistein has antihelmintic activity. … It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women [A14417].
Mixtures: OSMEGA 600 MG/400 IU/25 MG EFERVESAN TABLET, 30 ADET, CALCIDAY G 1200 MG/800 IU/50 MG EFERVESAN TABLET, 45 ADETCategories: Compounds used in a research, industrial, or household settingFomivirsen
go.drugbank.com/drugs/DB06759ApprovedWithdrawnIt is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised patients, including those with AIDS. … The drug was withdrawn by the FDA because while there was a high unmet need for drugs to treat CMV when the drug was initially discovered and developed due to the CMV arising in people with AIDS, the development
Categories: Compounds used in a research, industrial, or household settingAN-2718
go.drugbank.com/drugs/DB12810InvestigationalAn2718 has been used in trials studying Tinea Pedis.
Aloe vera leaf
go.drugbank.com/drugs/DB13906ApprovedInvestigationalWhile aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and pharmaceutical products. … Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands.
Corynebacterium diphtheriae
go.drugbank.com/drugs/DB09877ApprovedInvestigationalThe bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. … The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
Mixtures: Boostrix Injektionssuspension in einer Fertigspritze, Boostrix Polio - Injektionssuspension in einer FertigspritzeApraclonidine
go.drugbank.com/drugs/DB00964ApprovedInvestigationalApraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Categories: Sympathomimetics in Glaucoma Therapy