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Displaying results 1751 - 1760 of 10000 in total
  1. Drug

    Thioproperazine

    go.drugbank.com/drugs/DB01622
    Approved

    It is virtually without antiserotonin and hypotensive action and has no antihistaminic property. … Thioproperazine is a potent neuroleptic with antipsychotic properties.

    Synonyms: N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine-2-sulfonamide, N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamide
  2. Drug

    Indotecan

    go.drugbank.com/drugs/DB18752
    Investigational

    Categories: DNA Topoisomerases, Type I
  3. Drug

    Saxagliptin

    go.drugbank.com/drugs/DB06335
    ApprovedInvestigational

    Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.

  4. Drug

    Iberdomide

    go.drugbank.com/drugs/DB12101
    Investigational

    proteasome inhibitor and an immunomodulatory agent. … Iberdomide is an orally administered cereblon-modulating protein degrader (CELMoD) used to treat multiple myeloma.

  5. Drug

    acetylleucyl-leucyl-norleucinal

    go.drugbank.com/drugs/DB07558
    Experimental

    Synonyms: N-Ac-Leu-leu-norleucinal, N-acetylleucylleucylnorleucinalCategories: NF-kappa B, antagonists & inhibitors
  6. Drug

    Artemether

    go.drugbank.com/drugs/DB06697
    ApprovedInvestigational

    Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy.

  7. Drug

    Vamorolone

    go.drugbank.com/drugs/DB15114
    ApprovedInvestigational

    Vamorolone is a novel and fully synthetic glucocorticoid developed by Santhera Pharmaceuticals. … [L48676] Vamorolone is positioned as having a more tolerable adverse effect profile than other corticosteroids owing to its unique receptor binding profile,[A261976] thus providing an additional treatment

  8. Drug

    Ulobetasol

    go.drugbank.com/drugs/DB00596
    Approved

    Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].

  9. Drug

    Camptothecin

    go.drugbank.com/drugs/DB04690
    Investigational

    Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, <i>Camptotheca acuminata</i>. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I.

  10. Drug

    Melphalan flufenamide

    go.drugbank.com/drugs/DB16627
    ApprovedWithdrawn

    Melphalan flufenamide, also known as melflufen or J1, is a prodrug of [melphalan]. … [A230123] The increased potency makes melphalan flufenamide a treatment option for patients with relapsed or refractory multiple myeloma who have attempted at least 4 lines of therapy already.