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Azilsartan medoxomil
go.drugbank.com/drugs/DB08822ApprovedInvestigationalIt is used to treat hypertension as monotherapy or in combination with other antihypertensive drugs. It is also available in a combination product with [chlorthalidone]. … It is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesVilanterol
go.drugbank.com/drugs/DB09082ApprovedInvestigational[A259966] Additionally, vilanterol demonstrated a significantly longer duration of action than salmeterol, with the bronchodilator effect still apparent at 22h. … [A259961] Vilanterol was designed based on the salmeterol molecular scaffold, particularly as a antedrug analog of salmeterol modification by modifying the salmeterol molecule to create homochiral compounds
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesGadopentetic acid
go.drugbank.com/drugs/DB00789ApprovedInvestigationalA complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs.
Categories: Compounds used in a research, industrial, or household settingProducts: EMARAY IV ENJEKSIYONLUK COZELTI ICEREN FLAKON 10 ML, EMARAY IV ENJEKSIYONLUK COZELTI ICEREN FLAKON 15 MLMechlorethamine
go.drugbank.com/drugs/DB00888ApprovedInvestigationalA vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. … The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage.
Categories: Compounds used in a research, industrial, or household settingFosnetupitant
go.drugbank.com/drugs/DB14019ApprovedInvestigationalas major side effects. … ) as an alternative treatment option for patients experiencing chemotherapy-induced nausea and vomiting [L2631].
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 SubstratesVaricella zoster vaccine (recombinant)
go.drugbank.com/drugs/DB13924ApprovedInvestigationalOne of the most common complications associated with shingles is the development of Post-Herpetic Neuralgia (PHN), a persistant severe nerve pain that develops as a result of chronic pain from shingles … Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles.
Moxidectin
go.drugbank.com/drugs/DB11431ApprovedInvestigationalVet approvedMoxidectin differs by the absence of a disaccharide moiety on carbon 13, a substituted olefinic side chain at carbon 25 and a unique methoxime moiety at carbon 23. … Due to these modifications, moxidectin is classified as a second generation macrocyclic lactone.
Categories: Compounds used in a research, industrial, or household settingVigabatrin
go.drugbank.com/drugs/DB01080ApprovedInvestigationalAlthough administered as a racemic mixture, only the S(+) enantiomer is pharmacologically active. … [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was used extensively until 1997, when an association with vision loss became apparent.
Categories: Cytochrome P-450 CYP2C9 Inducers, Cytochrome P-450 Enzyme InducersBos taurus dander
go.drugbank.com/drugs/DB11020ApprovedBos taurus dander allergenic extract is used in allergenic testing.
Mixtures: Animal Allergens, AP Cattle Hair and Dander, Animal Allergens, AP Cattle Hair and DanderAmikacin
go.drugbank.com/drugs/DB00479ApprovedInvestigationalVet approvedAmikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A. … [L4680] Several forms of amikacin are used currently, including an intravenous (IV) or intramuscular (IM) injection.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexSynonyms: 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A