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Triazolam
go.drugbank.com/drugs/DB00897ApprovedInvestigationalWithdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. … Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Praziquantel
go.drugbank.com/drugs/DB01058ApprovedInvestigationalVet approved[A263206,A263211] Despite being approved since 1980, the exact mechanism of action is yet to be elucidated.[A263211] … [A263201] The efficacy of praziquantel in treating parasitic flatworms infection with low cost (~US$0.20 drug cost to treat a child) makes it an integral to WHO's plan to eliminate schistosomiasis by 2030
Cyclophosphamide
go.drugbank.com/drugs/DB00531ApprovedInvestigationalPrecursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. … It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep.
Indapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigationalThe most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. … agents may be required in order to achieve blood pressure targets.
Mixtures: PERINDO/IN RAT T 5/1.25, PERINDO/IN RAT T 5/1.25Products: COMPRIMIDOS RECUBIERTOS DE LIBERACION PROLONGADA, INDAPAMIDA 1.5 MG TABLETA DE LIBERACION PROLONGADAFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … [A179542] Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: FENTANYL ACTAVIS 25UG/H T, FENTANYL ACTAVIS 50UG/H TCefazolin
go.drugbank.com/drugs/DB01327ApprovedInvestigationalA semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Products: RECEF, İLKSEF 1000 MG IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ , 1 adet flakon ve 1 adet ampulNirmatrelvir
go.drugbank.com/drugs/DB16691ApprovedInvestigational[A234224] Without the activity of the SARS-CoV-2 3CL<sup>PRO</sup>, nonstructural proteins (including proteases) cannot be released to perform their functions, inhibiting viral replication. … mild-to-moderate COVID-19.
Ethambutol
go.drugbank.com/drugs/DB00330ApprovedInvestigationalEthambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in the treatment of pulmonary tuberculosis. … [L31743] Ethambutol was first described in the literature in 1961.[A229048] It was developed out of a need for therapies active against isoniazid resistant strains of _Mycobacterium tuberculosis_.
Mixtures: PRO TB 4Products: E-BUTOL TABLET 400 mgMaprotiline
go.drugbank.com/drugs/DB00934ApprovedMaprotiline may be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and major depressive disorder. … It differs from TCAs in that it does not appear to block serotonin reuptake.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDalbavancin
go.drugbank.com/drugs/DB06219ApprovedInvestigationalDalbavancin is a second-generation lipoglycopeptide antibiotic that was designed to improve on the natural glycopeptides currently available, such as vancomycin and teicoplanin [A4072, A4073]. … Dalbavancin acts by interfering with bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of nascent cell wall peptidoglycan and preventing cross-linking [FDA Label, F2356, A4072